Zaĭtseva N S, Teplinskaia L E, Tabagari D Z, Kaliberdina A F
Vestn Oftalmol. 1989 Jul-Aug;105(4):71-5.
Examinations of 30 patients with uveites, carried out by the method developed by Moretta et al., have revealed changes in T-lymphocyte subpopulations, mainly of the immunodeficiency type, with the reduction of the total T-lymphocyte count in 53.3% of patients and a significant decrease of the T mu/T gamma coefficient in 60% of patients. Stage II immunodeficiency status has been diagnosed in the majority of patients with generalized and anterior uveites. Stage II T-helper deficit has been most frequently detected in uveites coursing for 1-3 years with an exudative hemorrhagic component. The detection of the types and variant of immunoregulatory lymphocyte disorders helps choose the treatment strategy, including immunocorrecting drugs.
采用莫雷塔等人研发的方法对30例葡萄膜炎患者进行检查后发现，T淋巴细胞亚群出现变化，主要为免疫缺陷型，53.3%的患者总T淋巴细胞计数减少，60%的患者Tμ/Tγ系数显著降低。大多数全身性和前部葡萄膜炎患者被诊断为II期免疫缺陷状态。在病程为1 - 3年且伴有渗出性出血成分的葡萄膜炎患者中，最常检测到II期辅助性T细胞缺陷。检测免疫调节淋巴细胞紊乱的类型和变体有助于选择治疗策略，包括免疫纠正药物。
