The Research Clinic for Functional Disorders and Psychosomatics, Aarhus University Hospital, Aarhus, Denmark.
PLoS One. 2010 Mar 24;5(3):e9873. doi: 10.1371/journal.pone.0009873.
Hypochondriasis is prevalent in primary care, but the diagnosis is hampered by its stigmatizing label and lack of valid diagnostic criteria. Recently, new empirically established criteria for Health anxiety were introduced. Little is known about Health anxiety's impact on longitudinal outcome, and this study aimed to examine impact on self-rated health and health care costs.
METHODOLOGY/PRINCIPAL FINDINGS: 1785 consecutive primary care patients aged 18-65 consulting their family physicians (FPs) for a new illness were followed-up for two years. A stratified subsample of 701 patients was assessed by the Schedules for Clinical Assessment in Neuropsychiatry interview. Patients with mild (N = 21) and severe Health anxiety (N = 81) and Hypochondriasis according to the DSM-IV (N = 59) were compared with a comparison group of patients who had a well-defined medical condition according to their FPs and a low score on the screening questionnaire (N = 968). Self-rated health was measured by questionnaire at index and at three, 12, and 24 months, and health care use was extracted from patient registers. Compared with the 968 patients with well-defined medical conditions, the 81 severe Health anxiety patients and the 59 DSM-IV Hypochondriasis patients continued during follow-up to manifest significantly more Health anxiety (Whiteley-7 scale). They also continued to have significantly worse self-rated functioning related to physical and mental health (component scores of the SF-36). The severe Health anxiety patients used about 41-78% more health care per year in total, both during the 3 years preceding inclusion and during follow-up, whereas the DSM-IV Hypochondriasis patients did not have statistically significantly higher total use. A poor outcome of Health anxiety was not explained by comorbid depression, anxiety disorder or well-defined medical condition. Patients with mild Health anxiety did not have a worse outcome on physical health and incurred significantly less health care costs than the group of patients with a well-defined medical condition.
CONCLUSIONS/SIGNIFICANCE: Severe Health anxiety was found to be a disturbing and persistent condition. It is costly for the health care system and must be taken seriously, i.e. diagnosed and treated. This study supports the validity of recently introduced new criteria for Health anxiety.
疑病症在初级保健中很常见,但由于其带有污名化标签且缺乏有效的诊断标准,诊断受到阻碍。最近,新的健康焦虑症的实证诊断标准已经被引入。人们对健康焦虑症对纵向结果的影响知之甚少,本研究旨在检查其对自评健康和医疗保健费用的影响。
方法/主要发现:1785 名年龄在 18-65 岁之间的连续初级保健患者因新发疾病就诊于家庭医生(FP),并随访两年。对 701 名患者进行分层抽样,并通过神经精神病学临床评估计划访谈进行评估。根据 DSM-IV,将轻度健康焦虑症患者(N=21)、重度健康焦虑症患者(N=81)和疑病症患者(N=59)与 FP 明确诊断的患者(N=968)和根据筛查问卷得分较低的患者进行比较。使用问卷在基线和 3、12 和 24 个月时测量自评健康状况,从患者登记处提取医疗保健使用情况。与 968 名有明确诊断的患者相比,81 名重度健康焦虑症患者和 59 名疑病症患者在随访过程中继续表现出明显更多的健康焦虑症(Whiteley-7 量表)。他们的身体和心理健康相关功能自评也继续恶化(SF-36 的组成部分得分)。重度健康焦虑症患者在包括纳入前 3 年和随访期间在内的每年总医疗保健使用量增加了 41-78%,而疑病症患者的总使用量没有统计学上的显著增加。健康焦虑症的不良结局不能用共病抑郁症、焦虑症或明确的医学状况来解释。轻度健康焦虑症患者的身体健康状况没有恶化,并且比有明确诊断的患者的医疗保健费用明显减少。
结论/意义:发现重度健康焦虑症是一种令人不安且持续存在的疾病。它给医疗保健系统带来了巨大的负担,必须引起重视,即进行诊断和治疗。本研究支持最近引入的健康焦虑症新诊断标准的有效性。