Rask Mette Trollund, Ørnbøl Eva, Rosendal Marianne, Fink Per
From the Research Unit for General Practice, Department of Public Health (Rask, Rosendal), Aarhus University, Aarhus C, Denmark (Ørnbøl, Fink), and Research Clinic for Functional Disorders and Psychosomatics, Aarhus University Hospital, Aarhus N, Denmark.
Psychosom Med. 2017 Apr;79(3):345-357. doi: 10.1097/PSY.0000000000000405.
The upcoming International Classification of Diseases, 11th Revision for primary care use suggests inclusion of a new diagnostic construct, bodily (di)stress syndrome (BDS), for individuals with medically unexplained symptoms. We aimed to explore the long-term outcome of BDS in health care costs, work disability, and self-rated health.
Consecutive patients consulting their family physician for a new health problem were screened for physical and mental symptoms by questionnaires (n = 1785). A stratified subsample was examined with a standardized diagnostic interview (n = 701). Patients with single-organ BDS (n = 124) and multiorgan BDS (n = 35), and a reference group with a family physician-verified medical condition (n = 880) were included. All included patients completed a questionnaire at 3, 12, and 24 months of follow-up. Register data on health care costs and work disability were obtained after 2 and 10 years of follow-up, respectively.
Patients with BDS displayed poorer self-rated health and higher illness worry at index consultation and throughout follow-up than the reference group (p ≤ .001). The annual health care costs were higher in the BDS groups (2270 USD and 4066 USD) than in the reference group (1392 USD) (achieved significance level (ASL) ≤ 0.001). Both BDS groups had higher risk of sick leave during the first 2 years of follow-up (RRsingle-organ BDS = 3.0; 95% confidence interval [CI] = 1.8-5.0; RRmultiorgan BDS = 3.4; 95% CI = 1.5-7.5) and substantially higher risk of newly awarded disability pension than the reference group (HRsingle-organ BDS = 4.9; 95% CI = 2.8-8.4; HRmultiorgan BDS = 8.7; 95% CI = 3.7-20.7).
Patients with BDS have poor long-term outcome of health care costs, work disability, and subjective suffering. These findings stress the need for adequate recognition and management of BDS.
即将推出的供初级保健使用的《国际疾病分类》第11次修订版建议纳入一种新的诊断概念,即身体(双重)应激综合征(BDS),用于患有医学上无法解释症状的个体。我们旨在探讨BDS在医疗保健费用、工作残疾和自我评定健康方面的长期结果。
通过问卷调查对因新的健康问题向家庭医生咨询的连续患者进行身体和精神症状筛查(n = 1785)。使用标准化诊断访谈对分层子样本进行检查(n = 701)。纳入单器官BDS患者(n = 124)和多器官BDS患者(n = 35),以及经家庭医生核实患有疾病的参照组(n = 880)。所有纳入患者在随访3个月、12个月和24个月时完成一份问卷。分别在随访2年和10年后获取医疗保健费用和工作残疾的登记数据。
与参照组相比,BDS患者在初次会诊时及整个随访期间自我评定健康状况较差,疾病担忧程度较高(p≤0.001)。BDS组的年度医疗保健费用(2270美元和4066美元)高于参照组(1392美元)(达到的显著性水平(ASL)≤0.001)。在随访的前2年,两个BDS组病假风险均较高(单器官BDS的风险比(RR)= 3.0;95%置信区间[CI]=1.8 - 5.0;多器官BDS的RR = 3.4;95%CI = 1.5 - 7.5),且新获得残疾抚恤金的风险比参照组高得多(单器官BDS的风险比(HR)= 4.9;95%CI = 2.8 - 8.4;多器官BDS的HR = 8.7;95%CI = 3.7 - 20.7)。
BDS患者在医疗保健费用、工作残疾和主观痛苦方面的长期结果较差。这些发现强调了对BDS进行充分识别和管理的必要性。