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蓝色橡皮疱痣样痣综合征伴中枢神经系统症状迟发。

Blue rubber bleb nevus syndrome with late onset of central nervous system symptomatic involvement.

机构信息

Unità Operativa Di Neurologia, Azienda Ospedaliera-Universitaria, Verona, Italy.

出版信息

Neurol Sci. 2010 Aug;31(4):501-4. doi: 10.1007/s10072-010-0250-4. Epub 2010 Mar 30.

DOI:10.1007/s10072-010-0250-4
PMID:20352269
Abstract

Blue rubber bleb nevus syndrome is a rare vascular disorder characterized by cavernous angiomas of skin and other organs including the gastrointestinal tract. The central nervous system involvement is seldom reported, and neurological symptoms at onset in adulthood are extremely rare. Here, we describe a case of 82-year-old patient presenting multiple skin haemangiomas for some years, who was admitted for a brain hemorrhage. The MRI demonstrated the presence of multiple cavernous angiomas within the cerebral tissue.

摘要

蓝色橡皮疱痣样静脉畸形综合征是一种罕见的血管疾病,其特征为皮肤和其他器官(包括胃肠道)出现海绵状血管畸形。中枢神经系统受累很少见,成年起病的神经症状极其罕见。在此,我们描述了一例 82 岁患者,其多年来出现多处皮肤血管瘤,并因脑出血入院。MRI 显示脑内存在多个海绵状血管畸形。

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Blue Rubber Bleb Nevus Syndrome With Multiple Cavernoma-Like Lesions on MRI: A Familial Case Report and Literature Review.MRI显示蓝色橡皮疱痣综合征伴多发海绵状瘤样病变:1例家族性病例报告及文献复习
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Blue rubber bleb nevus syndrome: a case report and literature review.

本文引用的文献

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Blue rubber bleb nevus syndrome: novel lymphangiomatosis-like growth pattern within the uterus and immunohistochemical analysis.蓝色橡皮疱痣综合征:子宫内类似淋巴管瘤病的新型生长模式及免疫组化分析
Hum Pathol. 2009 Mar;40(3):413-7. doi: 10.1016/j.humpath.2008.05.019. Epub 2008 Sep 11.
2
Vascular malformation and hemangiomatosis syndromes: spectrum of imaging manifestations.血管畸形和血管瘤病综合征:影像表现谱
AJR Am J Roentgenol. 2008 May;190(5):1291-9. doi: 10.2214/AJR.07.2779.
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Diagnosis and treatment of blue rubber bleb nevus syndrome in children.
蓝色橡皮疱痣综合征:一例报告及文献复习
World J Gastroenterol. 2014 Dec 7;20(45):17254-9. doi: 10.3748/wjg.v20.i45.17254.
4
Endoscopic management of blue rubber bleb nevus syndrome: A case report.蓝色橡皮疱痣综合征的内镜治疗:一例报告
Exp Ther Med. 2013 Nov;6(5):1159-1162. doi: 10.3892/etm.2013.1303. Epub 2013 Sep 17.
5
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J Korean Surg Soc. 2012 Nov;83(5):316-20. doi: 10.4174/jkss.2012.83.5.316. Epub 2012 Oct 29.
儿童蓝色橡皮疱痣综合征的诊断与治疗
World J Pediatr. 2008 Feb;4(1):70-3. doi: 10.1007/s12519-008-0015-9.
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AJNR Am J Neuroradiol. 2008 Mar;29(3):494-500. doi: 10.3174/ajnr.A0847. Epub 2007 Nov 26.
6
Blue rubber bleb nevus syndrome: manifestations at computed tomography.蓝色橡皮疱痣综合征:计算机断层扫描表现
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[Contribution of molecular genetics in cavernous angiomas].
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