Elbashir Abdalla A, Aboul-Enein Hassan Y
Faculty of Science, Chemistry Department, University of Khartoum, PO Box 321, Khartoum, Sudan.
Biomed Chromatogr. 2010 Oct;24(10):1038-44. doi: 10.1002/bmc.1417.
Conductivity detection, which is universal in capillary electrophoresis (CE), has received considerable attention, since the introduction of the axial capacitively coupled contactless detector C(4)D in 1998. This detector is made of two electrodes which are placed cylindrically around the CE capillary and connected to the AC oscillator. The distance between the electrodes is the detection gap. In this review, applications of CE and MCE with C(4)D in pharmaceutical and biological analysis are presented.
自1998年轴向电容耦合非接触式检测器C(4)D问世以来,在毛细管电泳(CE)中普遍使用的电导检测受到了广泛关注。该检测器由两个电极组成,这两个电极围绕CE毛细管呈圆柱形放置,并连接到交流振荡器。电极之间的距离就是检测间隙。在这篇综述中,介绍了CE和MCE与C(4)D在药物和生物分析中的应用。