Joyce J A
AANA J. 1991 Apr;59(2):139-44.
Anabolic-androgenic steroids are used in the treatment of numerous medical conditions, including Fanconi's anemia, hypogonadism, hereditary angioedema, hypopituitarism and impotence. However, because of their potent anabolic properties, athletes began to use them to enhance body strength, size and endurance. Despite warnings from the medical and scientific communities of dangerous side effects such as Wilm's tumor, hepatocellular carcinoma, stroke and myocardial infarction, some athletes continue to use anabolic steroids. Among the numerous research publications, only one case report was found which related difficulties in anesthesia administration. This paper presents the physiologic changes associated with anabolic steroid ingestion and applies these changes to the administration of anesthesia.
合成代谢雄激素类固醇被用于治疗多种医学病症,包括范科尼贫血、性腺功能减退、遗传性血管性水肿、垂体功能减退和阳痿。然而,由于其强大的合成代谢特性,运动员开始使用它们来增强身体力量、增大肌肉块和提高耐力。尽管医学和科学界已发出警告,指出使用合成代谢雄激素类固醇会带来诸如肾母细胞瘤、肝细胞癌、中风和心肌梗死等危险副作用,但一些运动员仍继续使用。在众多研究出版物中,仅发现一篇病例报告涉及麻醉给药方面的困难。本文介绍了与摄入合成代谢类固醇相关的生理变化,并将这些变化应用于麻醉管理。