[鲜肿节风挥发油亚微乳的制备]
[Preparation of submicron emulsion of fresh Zhongjiefeng volatile oil].
作者信息
Wu Suxiang, Lv Guiyuan, Chen Suhong, Zhang Shengna, Zhao Lishan, Zhou Rihe, Zhou Huakang
机构信息
Zhejiang Chinese Medical University, Hangzhou 310053, China.
出版信息
Zhongguo Zhong Yao Za Zhi. 2009 Dec;34(24):3199-202.
OBJECTIVE
To prepare the submicron emulsion of fresh Zhongjiefeng volatile oil.
METHOD
The Zhongjiefeng volatile oil submicron emulsion was obtained after passing the elementary emulsion through a high pressure homogenizer. The physical and chemical stability of the emulsion was evaluated with the stability parameter of centrifugation, appearance of emulsion and the pH. The formulation and processing factors were optimized by single factor reviewing and orthogonal experimental design.
RESULT
By controlling various processing factors and optimizing formulation, the stable submicron emulsion of Zhongjiefeng volatile oil was prepared. Its mean particle diameter was 164-169 nm with PDI 0.084-0.107 and Zeta electric potential was -40 mV.
CONCLUSION
The formulation and preparation technique of the emulsion is reasonable.
目的
制备鲜肿节风挥发油亚微乳。
方法
初乳经高压均质机处理后得到肿节风挥发油亚微乳。通过离心稳定参数、乳剂外观及pH值对乳剂的理化稳定性进行评价。采用单因素考察和正交试验设计对处方及工艺因素进行优化。
结果
通过控制各种工艺因素并优化处方，制备出了稳定的肿节风挥发油亚微乳。其平均粒径为164 - 169nm，PDI为0.084 - 0.107，Zeta电位为 - 40mV。
结论
该乳剂的处方及制备工艺合理。
Zotero 插件