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一名儿童因产杀白细胞素的泛耐药金黄色葡萄球菌继发暴发性紫癜。

Purpura fulminans in a child secondary to Panton-Valentine leukocidin-producing Staphylococcus aureus.

作者信息

Hussain Abid, Robinson Gisela, Malkin Joanne, Duthie Mark, Kearns Angela, Perera Nelun

机构信息

Department of Clinical Microbiology, Leicester Royal Infirmary, University Hospitals of Leicester NHS Trust, Leicester LE1 5WW, UK.

Department of Child Health, Leicester Royal Infirmary, University Hospitals of Leicester NHS Trust, Leicester LE1 5WW, UK.

出版信息

J Med Microbiol. 2007 Oct;56(Pt 10):1407-1409. doi: 10.1099/jmm.0.47374-0.

DOI:10.1099/jmm.0.47374-0
PMID:17893182
Abstract

A case of purpura fulminans (PF) in a child secondary to infection with meticillin-sensitive Staphylococcus aureus (MSSA) encoding the Panton-Valentine leukocidin (PVL) toxin genes is presented. Occasional cases of PF have been documented secondary to S. aureus infection in adults, but, to the authors' knowledge, not in children. Here the first UK case of MSSA-PVL leading to PF is presented.

摘要

本文报告了一例儿童暴发性紫癜(PF),其继发于感染携带杀白细胞素(PVL)毒素基因的甲氧西林敏感金黄色葡萄球菌(MSSA)。成人中偶有文献记载PF继发于金黄色葡萄球菌感染,但据作者所知,儿童中尚无此类病例。本文首次报道了英国首例由MSSA-PVL导致PF的病例。

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Characterisation of the Virulence Factors and Genetic Types of Methicillin Susceptible Staphylococcus aureus from Patients and Healthy Individuals.
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