Department of Oral and Maxillofacial Surgery, New Jersey Dental School, University of Medicine and Dentistry of New Jersey, 110 Bergen St., Room B854, Newark, NJ 07103, USA.
J Am Dent Assoc. 2010 Apr;141(4):423-8. doi: 10.14219/jada.archive.2010.0194.
Oral submucous fibrosis (OSF) is an insidious precancerous disease affecting the oral cavity, pharynx and upper digestive tract. Its etiology is linked directly to betel nut use, which is common to the Indian subcontinent. With the increase in immigration of people from the Indian subcontinent to the United States, many American dental professionals will encounter this disease in the near future. The author provides a general overview of OSF.
The author provides a literature review of OSF, including its epidemiology, etiology, clinical presentation, histopathology and treatment modalities.
OSF is a precancerous oral disease linked definitively to the use of betel nut. It is endemic to people in the Indian subcontinent. Patients' primary complaint is progressive trismus. Treatment is based on disease severity.
OSF is a debilitating but preventable oral disease. Its incidence in the United States will increase as the South Asian immigrant population expands. Consequently, American dental professionals may encounter patients with this disease, and it is important that they are aware of it. In addition, for dental care professionals practicing in a South Asian American community, public health education is important to inform the population about the deleterious oral health effects of betel nut consumption.
口腔黏膜下纤维性变(OSF)是一种影响口腔、咽和上消化道的潜在癌前疾病。其病因与槟榔的使用直接相关,而槟榔在印度次大陆很常见。随着来自印度次大陆的移民不断涌入美国,许多美国牙科医生将在不久的将来遇到这种疾病。作者对 OSF 进行了概述。
作者对 OSF 进行了文献回顾,包括其流行病学、病因、临床表现、组织病理学和治疗方法。
OSF 是一种与咀嚼槟榔密切相关的癌前口腔疾病,在印度次大陆人群中流行。患者的主要主诉是进行性牙关紧闭。治疗取决于疾病的严重程度。
OSF 是一种使人虚弱但可预防的口腔疾病。随着南亚移民人口的增加,其在美国的发病率将会增加。因此,美国牙科医生可能会遇到患有这种疾病的患者,了解这种疾病非常重要。此外,对于在南亚裔美国人社区行医的牙科保健专业人员,开展公共卫生教育非常重要,以便向民众告知咀嚼槟榔对口腔健康的有害影响。