热休克蛋白 70 在神经元中的多效性作用。
Multifaceted role of heat shock protein 70 in neurons.
机构信息
Department of Physiology, University of Toronto, 3306 MSB, 1 King's College Circle, Toronto, Ontario, Canada M5S 1A8.
出版信息
Mol Neurobiol. 2010 Oct;42(2):114-23. doi: 10.1007/s12035-010-8116-6. Epub 2010 Apr 1.
PMID:20354811
Abstract
Heat shock protein 70 (Hsp70) plays important roles in neural protection from stress by assisting cellular protein folding. In this review we discuss the current understanding of inducible and constitutive Hsp70 in maintaining and protecting neuronal synaptic function under normal and stressed conditions.
摘要
热休克蛋白 70（Hsp70）在通过协助细胞蛋白折叠来保护神经免受应激方面发挥着重要作用。在这篇综述中，我们讨论了诱导型和组成型 Hsp70 在维持和保护神经元突触功能方面的现有认识，包括在正常和应激条件下。
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