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蓖麻毒素中毒与法医毒物学。

Ricin poisoning and forensic toxicology.

机构信息

Institute of Forensic Medicine, University Bonn, Stiftsplatz 12, 53111 Bonn, Germany.

出版信息

Drug Test Anal. 2009 Apr;1(4):184-91. doi: 10.1002/dta.27.

Abstract

Ricin is one of the most fascinating poisons due to its high toxicity: as little as 500 microg can kill an adult. It gained fame by its use in the so-called 'umbrella murder' to kill the Bulgarian dissident Georgi Markov in 1978. Ricin also became known as a potential bio-terror agent to which people could be exposed through the air, food, or water. The origin, biochemistry, toxicity, and analytical procedures for the determination of ricin are summarized. The homicide of Markov is described as well as recent cases of criminal ricin use.

摘要

蓖麻毒素是最令人着迷的毒药之一,因为它的毒性很高:只需 500 微克即可杀死一个成年人。它在 1978 年所谓的“雨伞谋杀案”中被用于杀害保加利亚持不同政见者乔治·马尔科夫而声名狼藉。蓖麻毒素也被认为是一种潜在的生物恐怖剂,人们可能会通过空气、食物或水接触到它。本文总结了蓖麻毒素的来源、生物化学、毒性和分析程序。还描述了马尔科夫的凶杀案以及最近几起刑事蓖麻毒素使用案件。

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