口服蓖麻子后发生的蓖麻毒素中毒：一例报告及文献综述
Ricin poisoning after oral ingestion of castor beans: A case report and literature review.
作者信息
Benamor Mouna, Gharbi Emna, Bouzid Sirine, Chakroun-Walha Olfa, Rekik Noureddine
机构信息
Universite de Sfax, Faculte de Medecine de Sfax, Sfax, Tunisia.
出版信息
Afr J Emerg Med. 2020 Dec;10(4):274-276. doi: 10.1016/j.afjem.2020.06.002. Epub 2020 Jul 11.
INTRODUCTION
1000 ricin poisoning cases secondary to intentional castor bean consumption have been reported in the literature since the late 1800s. The lethality of ricin poisoning after oral ingestion is determined by a few factors.
CASE REPORT
We present a case that highlights the erratic absorption of ricin after accidental oral ingestion. On admission, the physical examination found a somnolent patient, with miosis, and a generalized abdominal tenderness. Her blood tests showed metabolic acidosis. Thanks to her early management, the discharge was possible three days later.
DISCUSSION
The toxicity of ricin is dependent on the dose delivered and the route of the exposure. Supportive care is the mainstay of treatment. As shown in our case, early management is crucial for a good outcome.
引言
自19世纪末以来，文献中已报道了1000多起因故意食用蓖麻子导致的蓖麻毒素中毒病例。口服摄入后蓖麻毒素中毒的致死率取决于几个因素。
病例报告
我们报告一例病例，该病例突出了意外口服摄入蓖麻毒素后吸收不稳定的情况。入院时，体格检查发现患者嗜睡、瞳孔缩小且全腹压痛。她的血液检查显示代谢性酸中毒。由于早期治疗，三天后患者得以出院。
讨论
蓖麻毒素的毒性取决于给药剂量和接触途径。支持性治疗是主要的治疗方法。如我们的病例所示，早期治疗对于取得良好预后至关重要。
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