Department of Chemistry and YJ-Science and Technology Research Center, The American University in Cairo, Cairo, Egypt.
Drug Test Anal. 2009 Jul;1(7):311-22. doi: 10.1002/dta.52.
Gene doping, the abuse of gene therapy for illicit athletic enhancement, is perceived as a coming threat and is a prime concern to the anti-doping community. This doping technique represents a significant ethical challenge and there are concerns regarding its safety for athletes. This article presents the basics of gene doping, potential strategies for its detection and the role of promising new technologies in aiding detection efforts. These include the use of lab-on-a-chip techniques as well as nanoparticles to enhance the performance of current analytical methods and to develop new doping detection strategies.
基因兴奋剂，即滥用基因治疗进行非法的运动员增强，被视为一种即将到来的威胁，也是反兴奋剂界的主要关注点。这种兴奋剂技术代表了一个重大的伦理挑战，人们对其对运动员的安全性也存在担忧。本文介绍了基因兴奋剂的基础知识，以及针对其检测的潜在策略，以及有前途的新技术在辅助检测工作中的作用。这些包括使用芯片实验室技术和纳米粒子来增强当前分析方法的性能，并开发新的兴奋剂检测策略。
