School of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.
Med Sci Monit. 2010 Apr;16(4):HY3-5.
HIV cognitive impairments are a common occurrence. Although some of the etiologies of such cognitive impairments are understood, some of the causes are not always straightforward because adults with HIV represent a very heterogenous population. Unfortunately, many of the studies that investigate cognition in this population rely on convenience samples of HIV-positive adults who may lack cognitive stimulation due to poor education or unemployment, both of which can promote negative neuroplasticity. By the same token, other adults with HIV may be cognitively stimulated by their work, educational pursuits, and intellectual interests which may promote positive neuroplasticity which may be protective against cognitive impairments. Implications for how this impacts research as well as prevention and intervention of cognitive impairments are posited.
HIV 认知障碍较为常见。虽然已经了解了一些导致此类认知障碍的病因，但有些病因并不总是那么明确，因为 HIV 感染者群体非常多样化。不幸的是，许多研究 HIV 感染者认知功能的研究都依赖于方便抽样的 HIV 阳性成年人，这些成年人可能由于受教育程度低或失业而缺乏认知刺激，而这两者都会促进负性神经可塑性。同样地，其他 HIV 感染者可能会因为工作、教育追求和智力兴趣而受到认知刺激，这可能会促进正性神经可塑性，从而对认知障碍起到保护作用。本文提出了这对研究以及认知障碍的预防和干预的影响。
