Rice A S, Pither C E, Tucker G T
Department of Anaesthetics, St. Thomas' Hospital, London.
Anaesthesia. 1991 May;46(5):354-7. doi: 10.1111/j.1365-2044.1991.tb09542.x.
The plasma concentrations of bupivacaine and the latency and duration of anaesthesia after supraclavicular block with 30 ml of 0.5% bupivacaine were measured in 10 patients with chronic renal failure and in 10 patients with normal renal function. No significant difference was found between the two groups in respect of pharmacokinetic parameters, or in block latency or duration.
对10例慢性肾功能衰竭患者和10例肾功能正常的患者，测定了用30毫升0.5%布比卡因进行锁骨上阻滞术后布比卡因的血浆浓度以及麻醉潜伏期和持续时间。两组在药代动力学参数、阻滞潜伏期或持续时间方面均未发现显著差异。
