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健康相关生活质量在卒中后是否得到改善?1996 年至 2005 年加拿大卒中患者健康效用指数的比较。

Is health-related quality of life improving after stroke? A comparison of health utilities indices among Canadians with stroke between 1996 and 2005.

机构信息

School of Population and Public Health, University of British Columbia, Vancouver, British Columbia, Canada.

出版信息

Stroke. 2010 May;41(5):996-1000. doi: 10.1161/STROKEAHA.109.576678. Epub 2010 Apr 1.

Abstract

BACKGROUND AND PURPOSE

Recent innovations in diagnosis, management, and rehabilitation have resulted in measurable improvements in clinical and functional outcomes after acute stroke. However, whether gains in health-related quality of life after stroke have also occurred is not well characterized. Using 2 Canadian population surveys, the purpose of this study was to identify changes in health-related quality of life in individuals with stroke from 1996 to 2005.

METHODS

Data from the public use files of the National Population Health Survey, Cycle 2 (1996), and the Canadian Community Health Survey, Cycle 3.1. (2005), were used. A total of 847 individuals with stroke were included. Self-reported information on health status based on the Health Utilities Index Mark 3 was used to generate single-attribute and overall health-related quality of life scores. Analysis of covariance and multiple logistic regression were used to determine the relationship between survey year and poststroke impairment adjusting for demographic variables and clinical comorbidities.

RESULTS

A statistically significant and clinically important reduction in mean overall Health Utilities Index Mark 3 scores was observed for respondents with stroke from 1996 to 2005. In addition, 2 of the 8 single-attribute Health Utilities Index Mark 3 domains showed a significant change between survey years. Significantly more individuals with stroke reported dexterity and cognitive impairment in 2005 compared with respondents in 1996, indicating reduced health-related quality of life for these domains.

CONCLUSIONS

Despite improvements in medical management, quality of life is not improving after stroke in the Canadian population. These findings are useful to generate hypotheses about the impact of advances in management on quality of life after stroke and identify specific domains that may benefit from future study in stroke populations.

摘要

背景与目的

近年来,在急性中风的诊断、治疗和康复方面的创新取得了临床和功能结果的显著改善。然而,中风后健康相关生活质量是否也有所提高,目前还没有得到很好的描述。本研究使用了两项加拿大人群调查,旨在确定 1996 年至 2005 年中风患者健康相关生活质量的变化。

方法

使用国家人口健康调查公共使用文件,循环 2(1996 年)和加拿大社区健康调查,循环 3.1(2005 年)的数据。共纳入 847 例中风患者。使用基于健康效用指数标记 3 的自我报告健康状况信息来生成单一属性和整体健康相关生活质量评分。使用协方差分析和多逻辑回归来确定调整人口统计学变量和临床合并症后,调查年份与中风后残疾之间的关系。

结果

从 1996 年到 2005 年,中风患者的平均总体健康效用指数标记 3 评分有统计学意义和临床意义的降低。此外,8 个单一属性健康效用指数标记 3 域中的 2 个在调查年份之间发生了显著变化。2005 年与 1996 年相比,更多的中风患者报告了灵活性和认知障碍,表明这些领域的健康相关生活质量下降。

结论

尽管医疗管理有所改善,但加拿大人口中风后的生活质量并未改善。这些发现有助于提出关于管理进步对中风后生活质量影响的假设,并确定中风人群中可能需要进一步研究的特定领域。

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