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新型移动致动器式机电全人工心脏的研发

Development of a new moving-actuator type electromechanical total artificial heart.

作者信息

Min B G, Kim H C, Lee S H, Kim I Y, Kim J W, Choi J W, Kim J T, Jung D Y

机构信息

Department of Biomedical Engineering, College of Medicine, Seoul National University, Korea.

出版信息

Artif Organs. 1991 Apr;15(2):144-6. doi: 10.1111/j.1525-1594.1991.tb00773.x.

DOI:10.1111/j.1525-1594.1991.tb00773.x
PMID:2036063
Abstract

A new type of electromechanical total artificial heart based on a moving-actuator mechanism was developed to decrease the total pump size and to improve the fitting characteristic of the pump to atrial remnants and arterial vessels. The blood pump consists of three major parts: right and left blood sacs and a moving pump actuator between two sacs. The total weight is 810 g and the volume of the pump is 770 ml. The actuator rolls back and forth on a circular track, producing alternating blood ejection. The pump performance was evaluated in mock circulation and animal implant experiments. The pump was implanted for 100 h in a calf (approximately 100 kg) with a stable hemodynamic state until accidental (electrical short circuit) death.

摘要

基于移动驱动机构开发了一种新型机电式全人工心脏,以减小泵的整体尺寸,并改善泵与心房残余组织和动脉血管的适配特性。血泵由三个主要部分组成:左右血囊以及位于两个血囊之间的移动泵驱动装置。总重量为810克,泵的体积为770毫升。驱动装置在圆形轨道上来回滚动,产生交替的血液喷射。在模拟循环和动物植入实验中对泵的性能进行了评估。该泵在一头小牛(约100千克)体内植入了100小时,血流动力学状态稳定,直至因意外(电气短路)死亡。

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