• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

遗传性出血性毛细血管扩张症中的“假性肝硬化”

'Pseudocirrhosis' in hereditary haemorrhagic telangiectasia.

作者信息

Cooney T, Sweeney E C, Coll R, Greally M

出版信息

J Clin Pathol. 1977 Dec;30(12):1134-41. doi: 10.1136/jcp.30.12.1134.

DOI:10.1136/jcp.30.12.1134
PMID:203609
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC476696/
Abstract

Telangiectasia-associated hepatic fibrosis (TAHF) in a 68-year-old woman with hereditary haemorrhagic telangiectasia (HHT) is described. The patient died of oat-cell carcinoma of the lung. In addition to the structural alterations which have been described previously in HHT, the liver exhibited focal midlobular hepatocytic necrosis and tumour metastases. The possibility that treatment of HHT was causally related to some of the hepatic abnormalities found in our patient and the differentiation of TAHF from true cirrhosis are discussed.

摘要

本文描述了一名68岁患有遗传性出血性毛细血管扩张症（HHT）的女性患者的毛细血管扩张相关肝纤维化（TAHF）。该患者死于肺燕麦细胞癌。除了先前在HHT中所描述的结构改变外，肝脏还表现出局灶性小叶中部肝细胞坏死和肿瘤转移。文中讨论了HHT的治疗与我们患者所发现的一些肝脏异常之间存在因果关系的可能性，以及TAHF与真性肝硬化的鉴别。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28f5/476696/f4d102fa724e/jclinpath00170-0049-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28f5/476696/7deff5a00220/jclinpath00170-0046-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28f5/476696/dc94325c1e9d/jclinpath00170-0046-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28f5/476696/e07ee97de7e9/jclinpath00170-0047-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28f5/476696/ceac0dc57f73/jclinpath00170-0047-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28f5/476696/16c8bd18a5bd/jclinpath00170-0048-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28f5/476696/23225985e4b1/jclinpath00170-0048-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28f5/476696/f4d102fa724e/jclinpath00170-0049-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28f5/476696/7deff5a00220/jclinpath00170-0046-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28f5/476696/dc94325c1e9d/jclinpath00170-0046-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28f5/476696/e07ee97de7e9/jclinpath00170-0047-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28f5/476696/ceac0dc57f73/jclinpath00170-0047-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28f5/476696/16c8bd18a5bd/jclinpath00170-0048-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28f5/476696/23225985e4b1/jclinpath00170-0048-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/28f5/476696/f4d102fa724e/jclinpath00170-0049-a.jpg

相似文献

1
'Pseudocirrhosis' in hereditary haemorrhagic telangiectasia.遗传性出血性毛细血管扩张症中的“假性肝硬化”
J Clin Pathol. 1977 Dec;30(12):1134-41. doi: 10.1136/jcp.30.12.1134.
2
Hepatic telangiectasia and cirrhosis.肝毛细血管扩张症和肝硬化。
J Clin Gastroenterol. 1988 Feb;10(1):111-4. doi: 10.1097/00004836-198802000-00026.
3
Monstrous ascites in hereditary haemorrhagic telangiectasia.遗传性出血性毛细血管扩张症中的巨大腹水
Scand J Gastroenterol. 1995 Jan;30(1):92-4. doi: 10.3109/00365529509093242.
4
Liver transplantation for hepatic arteriovenous malformation in hereditary haemorrhagic telangiectasia.遗传性出血性毛细血管扩张症肝动静脉畸形的肝移植治疗
J Hepatol. 1995 May;22(5):586-90. doi: 10.1016/0168-8278(95)80455-2.
5
The pathology of acute hepatic disintegration in hereditary haemorrhagic telangiectasia.遗传性出血性毛细血管扩张症中急性肝崩解的病理学
Histopathology. 2003 Mar;42(3):265-9. doi: 10.1046/j.1365-2559.2003.01579.x.
6
Hereditary haemorrhagic telangiectasia: to transplant or not to transplant - is there a right time for liver transplantation?遗传性出血性毛细血管扩张症：移植还是不移植——肝移植的时机是否恰当？
Liver Int. 2016 Dec;36(12):1735-1740. doi: 10.1111/liv.13187.
7
Hereditary hemorrhagic telangiectasia with malignant lymphoma. An autopsy case.遗传性出血性毛细血管扩张症合并恶性淋巴瘤。1例尸检病例。
Acta Pathol Jpn. 1988 Mar;38(3):383-91. doi: 10.1111/j.1440-1827.1988.tb02310.x.
8
Liver resection in patients with hepatic hereditary hemorrhagic telangiectasia.肝切除术治疗遗传性出血性毛细血管扩张症患者。
Dig Surg. 2013;30(4-6):410-4. doi: 10.1159/000351446. Epub 2013 Nov 5.
9
Three-dimensional organization of the hepatic microvasculature in hereditary hemorrhagic telangiectasia.遗传性出血性毛细血管扩张症中肝微血管的三维结构
Arch Pathol Lab Med. 2001 Sep;125(9):1219-23. doi: 10.5858/2001-125-1219-TDOOTH.
10
Identifying the presence of clinically significant hepatic involvement in hereditary haemorrhagic telangiectasia using a simple clinical scoring index.使用简单的临床评分指数识别遗传性出血性毛细血管扩张症中具有临床意义的肝受累情况。
J Hepatol. 2014 Jul;61(1):124-31. doi: 10.1016/j.jhep.2014.02.028. Epub 2014 Mar 6.

引用本文的文献

1
Current guidelines for diagnosis and management of hepatic involvement in hereditary hemorrhagic teleangiectasia.遗传性出血性毛细血管扩张症肝脏受累的诊断和管理现行指南。
World J Hepatol. 2023 May 27;15(5):675-687. doi: 10.4254/wjh.v15.i5.675.
2
The Role of Liver Imaging in Hereditary Hemorrhagic Telangiectasia.肝脏成像在遗传性出血性毛细血管扩张症中的作用
J Clin Med. 2020 Nov 21;9(11):3750. doi: 10.3390/jcm9113750.
3
Lactulose to the Rescue: A Case of Toxic Hepatic Encephalopathy Caused by Portosystemic Shunting and Epistaxis in a Patient with Hereditary Hemorrhagic Telangiectasia.

本文引用的文献

1
The rarity of intrahepatic metastasis in cirrhosis of the liver. A statistical explanation with some comments on the interpretation of necropsy data.肝内转移在肝硬化中的罕见性。基于尸检数据解读的统计学解释及一些评论
Am J Pathol. 1961 Dec;39(6):739-46.
2
HEPATIC ARTERY ANEURYSM WITH PORTAL VEIN FISTULA IN A PATIENT WITH FAMILIAL HEREDITARY TELANGIECTASIA.一名患有家族遗传性毛细血管扩张症的患者出现肝动脉瘤伴门静脉瘘
Ann Surg. 1964 Mar;159(3):362-7.
3
FAMILIAL HAEMORRHAGIC TELANGIECTASIA. 20 CASES TREATED WITH SYSTEMIC OESTROGEN.
乳果糖来救场：一例因门体分流和鼻出血导致的中毒性肝性脑病，患者患有遗传性出血性毛细血管扩张症。
Case Reports Hepatol. 2019 Mar 26;2019:7573408. doi: 10.1155/2019/7573408. eCollection 2019.
4
Optimal management of hereditary hemorrhagic telangiectasia.遗传性出血性毛细血管扩张症的优化管理
J Blood Med. 2014 Oct 15;5:191-206. doi: 10.2147/JBM.S45295. eCollection 2014.
5
Hepatic and pancreatic involvement in hereditary hemorrhagic telangiectasia: quantitative and qualitative evaluation with 64-section CT in asymptomatic adult patients.遗传性出血性毛细血管扩张症的肝脏和胰腺累及：64 层 CT 对无症状成年患者的定量和定性评估。
Eur Radiol. 2012 Jan;22(1):161-70. doi: 10.1007/s00330-011-2243-y. Epub 2011 Aug 23.
6
Clinical outcome of transfemoral embolisation in patients with arteriovenous malformations of the liver in hereditary haemorrhagic telangiectasia (Weber-Rendu-Osler disease).遗传性出血性毛细血管扩张症（韦-伦-奥氏病）患者肝动静脉畸形经股动脉栓塞术的临床结果
Gut. 1998 Jan;42(1):123-6. doi: 10.1136/gut.42.1.123.
Q J Med. 1964 Jan;33:25-38.
4
Liver fibrosis in hereditary hemorrhagic telangiectasia. Fibrosis of diffuse insular character.遗传性出血性毛细血管扩张症中的肝纤维化。弥漫性岛状纤维化。
Arch Pathol. 1962 Jul;74:66-72.
5
Nodular regenerative hyperplasia of the liver.肝脏结节状再生性增生
Am J Pathol. 1959 Sep-Oct;35(5):943-53.
6
Multiple small arteriovenous fistulae of the lungs.
Am J Pathol. 1956 Sep-Oct;32(5):927-43.
7
On the pathogenesis of hepatic changes in teleangiectasia hereditaria haemorrhagica (morbus Osler-Rendu-Weber).遗传性出血性毛细血管扩张症（奥斯勒-伦杜-韦伯病）肝脏病变的发病机制
Acta Pathol Microbiol Scand. 1954;35(4):332-8. doi: 10.1111/j.1699-0463.1954.tb00877.x.
8
Hereditary hemorrhagic telangiectasia; nine cases in one Negro family, with special reference to hepatic lesions.遗传性出血性毛细血管扩张症；一个黑人家庭中的9例病例，特别提及肝脏病变
Am J Med. 1954 Jul;17(1):41-9. doi: 10.1016/0002-9343(54)90142-4.
9
Hepatic telangiectases and portosystemic encephalopathy in Osler-Weber-Rendu disease.
Gastroenterology. 1968 May;54(5):929-32.
10
Angiodysplasias of the abdominal viscera associated with hereditary hemorrhagic telangiectasia.与遗传性出血性毛细血管扩张症相关的腹腔脏器血管发育异常。
Am J Roentgenol Radium Ther Nucl Med. 1968 Apr;102(4):783-9.