Department of Orthopaedic Surgery, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany.
Arch Orthop Trauma Surg. 2010 Jun;130(6):775-80. doi: 10.1007/s00402-010-1096-1. Epub 2010 Apr 4.
Fractures are a common problem for patients with spinal muscular atrophy (SMA).
A total of 131 patients with proximal SMA with an average age of 13.2 +/- 9.2 years (0.7-65.6) were evaluated retrospectively. In 60 patients 94 different fractures were observed. The group consisted of 11 patients with type Ib, 81 with type II, 33 with type IIIa, 4 with IIIb and 2 with type IV. 38 of 81 SMA II patients and 17 of 33 SMA IIIa patients had suffered fractures at an average age of 8.3 +/- 5.3 years (0.0-25.1) (SMA II) and 9.3 +/- 6.0 years (0.0-22.1) (SMA IIIa).
The most frequent fractures were of the femur (50), usually distal, of the lower leg and ankle (15), and upper arm (9). The distribution of fractures was different in SMA II and SMA IIIa. Most of the fractures could be treated conservatively. Only two femoral shaft fractures, one upper arm and a lower arm fracture were treated surgically by osteosynthesis.
Competent fracture treatment is an important part of the orthopaedic care of SMA patients.
骨折是脊髓性肌萎缩症（SMA）患者的常见问题。
共回顾性评估了 131 例近端 SMA 患者，平均年龄为 13.2 +/- 9.2 岁（0.7-65.6）。在 60 例患者中观察到 94 处不同的骨折。该组包括 11 例 Ib 型、81 例 II 型、33 例 IIIa 型、4 例 IIIb 型和 2 例 IV 型。81 例 SMA II 患者中有 38 例和 33 例 SMA IIIa 患者中有 17 例在平均年龄 8.3 +/- 5.3 岁（0.0-25.1）（SMA II）和 9.3 +/- 6.0 岁（0.0-22.1）（SMA IIIa）时发生骨折。
最常见的骨折是股骨（50 例），通常是远端的小腿和踝关节（15 例）和上臂（9 例）骨折。SMA II 和 SMA IIIa 的骨折分布不同。大多数骨折可以保守治疗。只有 2 例股骨干骨折、1 例上臂骨折和 1 例前臂骨折通过内固定术进行了手术治疗。
熟练的骨折治疗是 SMA 患者矫形护理的重要组成部分。
