功能性精神病中的抗脑抗体。
Anticerebral antibodies in functional psychoses.
作者信息
Shima S, Yano K, Sugiura M, Tokunaga Y
机构信息
Department of Neuropsychiatry, School of Medicine, Keio University, Tokyo, Japan.
出版信息
Biol Psychiatry. 1991 Feb 15;29(4):322-8. doi: 10.1016/0006-3223(91)90217-a.
Anticerebral antibodies to rabbit brain were investigated by the indirect immunofluorescence method in the sera of 44 schizophrenics and 52 depressives diagnosed according to DSM-III-R, and of 54 healthy volunteers. Four types of staining pattern were observed: type A (nerve cells), type B (blood vessels), type C (nuclei), and type D (glial cells); 34.1% of schizophrenics (27.3% after the absorption with rabbit liver acetone powder) showed type A, as compared with 3.8% (1.9% after the absorption) of depressives and with none of the controls.
采用间接免疫荧光法，对44例根据《精神疾病诊断与统计手册》第三版修订本（DSM-III-R）诊断的精神分裂症患者、52例抑郁症患者以及54名健康志愿者血清中的抗兔脑抗体进行了研究。观察到四种染色模式：A型（神经细胞）、B型（血管）、C型（细胞核）和D型（神经胶质细胞）；34.1%的精神分裂症患者呈现A型（用兔肝丙酮粉吸收后为27.3%），相比之下，抑郁症患者中呈现A型的比例为3.8%（吸收后为1.9%），而对照组中无人呈现A型。
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