Zerbini M C, Vianna M R, Ribeiro D, Ayoub A A, Porta G, Sesso A
Department of Pathology, Faculty of Medicine, University of São Paulo, Brazil.
J Submicrosc Cytol Pathol. 1991 Jan;23(1):141-5.
Electron microscopic examination of an infantile hemangioendothelioma (IHE) type I of the liver, appearing in a five month old child, showed a high density of pericytes in the walls of the neoplastic vessels. These vessels, in part of the IHE patients, establish an important arteriovenous shunt leading to high output, congestive cardiac failure. It is unclear whether functions ascribed to pericytes, such as participation in microvascular contractility or as suppressors of endothelial cell proliferation are involved in two noteworthy aspects of the present case. The child exhibited no congestive heart failure and the multiple nodular lesions underwent spontaneous regression.
对一名5个月大儿童所患的I型婴儿肝血管内皮瘤（IHE）进行电子显微镜检查，结果显示肿瘤血管壁中的周细胞密度很高。在部分IHE患者中，这些血管会形成重要的动静脉分流，导致高输出量充血性心力衰竭。目前尚不清楚周细胞的功能，如参与微血管收缩或作为内皮细胞增殖的抑制因子，是否与本病例的两个值得关注的方面有关。该患儿未出现充血性心力衰竭，且多个结节性病变自发消退。
