Feldman P S, Shneidman D, Kaplan C
Cancer. 1978 Aug;42(2):521-7. doi: 10.1002/1097-0142(197808)42:2<521::aid-cncr2820420221>3.0.co;2-0.
A two-month-old female presented with hepatomegaly 5 cm below the right costal margin. Resection of a 6 cm hepatic mass demonstrated an infantile hemangioendotheliom (IHE). This documents for the first time the ultrastructural features of an IHE of the liver. Ultrastructural examination showed large numbers of vascular channels of varying sizes lined by abnormal endothelial cells. An incomplete basal lamina separated the endothelial cells from the extracellular material and there were no associated pericytes. The intervascular area contained abundant collagen fibers, fibrils, and cells ultrastructurally similar to fibroblasts. The relationship of structure to certain clinical features of this lesion is discussed.
一名两个月大的女婴，右肋缘下5厘米处肝脏肿大。切除一个6厘米的肝脏肿块后显示为婴儿型血管内皮瘤（IHE）。本文首次记录了肝脏IHE的超微结构特征。超微结构检查显示大量大小不一的血管通道，内衬异常内皮细胞。不完整的基膜将内皮细胞与细胞外物质分隔开，且无相关周细胞。血管间区域含有丰富的胶原纤维、原纤维以及超微结构上类似于成纤维细胞的细胞。本文还讨论了该病变的结构与某些临床特征之间的关系。
