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奇异变形杆菌(ATCC 49565)的荚膜结构。

Capsule structure of Proteus mirabilis (ATCC 49565).

作者信息

Beynon L M, Dumanski A J, McLean R J, MacLean L L, Richards J C, Perry M B

机构信息

Institute for Biological Sciences, National Research Council, Ottawa, Ontario, Canada.

出版信息

J Bacteriol. 1992 Apr;174(7):2172-7. doi: 10.1128/jb.174.7.2172-2177.1992.

Abstract

Proteus mirabilis 2573 (ATCC 49565) produces an acidic capsular polysaccharide which was shown from glycose analysis, carboxyl reduction, methylation, periodate oxidation, and the application of one dimensional and two-dimensional high-resolution nuclear magnetic resonance techniques to be a high-molecular-weight polymer of branched trisaccharide units composed of 2-acetamido-2-deoxy-D-glucose (N-acetyl-D-glucosamine), 2-acetamido-2,6-dideoxy-L-galactose (N-acetyl-L-fucosamine), and D-glucuronic acid, having the structure: [formula: see text] P. mirabilis 2573 also produces an O:6 serotype lipopolysaccharide in which the O-chain component has the same structure as the homologous capsular polysaccharide. This is the first report of a defined capsular polysaccharide in this bacterial genus.

摘要

奇异变形杆菌2573(ATCC 49565)产生一种酸性荚膜多糖,通过葡萄糖分析、羧基还原、甲基化、高碘酸盐氧化以及一维和二维高分辨率核磁共振技术的应用表明,它是一种由2-乙酰氨基-2-脱氧-D-葡萄糖(N-乙酰-D-葡糖胺)、2-乙酰氨基-2,6-二脱氧-L-半乳糖(N-乙酰-L-岩藻糖胺)和D-葡萄糖醛酸组成的支链三糖单元的高分子量聚合物,其结构为:[化学式:见原文]。奇异变形杆菌2573还产生一种O:6血清型脂多糖,其中O链成分与同源荚膜多糖具有相同的结构。这是关于该细菌属中一种明确的荚膜多糖的首次报道。

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