[不同年龄段人群中的慢性胃炎与疱疹感染]

[Chronic gastritis and herpetic infections in subjects of different ages].

作者信息

Krulevskiĭ V A, Petrovskiĭ A N, Anichkov N M, Novikova V P

出版信息

Arkh Patol. 2010 Jan-Feb;72(1):33-5.

PMID:20369583

Abstract

Gastric mucosal biopsy specimens were immunohistochemically studied to detect the antigens of herpes simplex virus, cytomegalovirus, and Epstein-Barr virus (EB ) in 103 children aged 7-17 years and 49 adults aged 18-78 years who suffered from morphologically verified chronic gastritis. Gastric mucosal virus antigens were found in 70% of the children (including EBV in 44.8%; herpes simplex virus in 34.9%, cytomegalovirus in 16.5%; concurrence of two and three infections in 22.3 and 1.9%, respectively) and in 65.3% of the adults (EBV in 408%; herpes simplex virus in 26.5%, cytomegalovirus in 18.4%; concurrence of two and three infections in 26.3 and 2%, respectively). It was shown that herpes viruses may play an etiological role in the development of chronic gastritis in children and adults.

摘要

对103名7至17岁儿童和49名18至78岁成年人的胃黏膜活检标本进行免疫组织化学研究，这些患者均患有经形态学证实的慢性胃炎，以检测单纯疱疹病毒、巨细胞病毒和爱泼斯坦-巴尔病毒（EB）的抗原。在70%的儿童中发现了胃黏膜病毒抗原（包括44.8%的EB病毒；34.9%的单纯疱疹病毒，16.5%的巨细胞病毒；两种和三种感染同时存在的分别为22.3%和1.9%），在65.3%的成年人中发现了胃黏膜病毒抗原（408%的EB病毒；26.5%的单纯疱疹病毒，18.4%的巨细胞病毒；两种和三种感染同时存在的分别为26.3%和2%）。结果表明，疱疹病毒可能在儿童和成人慢性胃炎的发生中起病因学作用。