Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Ocul Immunol Inflamm. 2010 Apr;18(2):121-6. doi: 10.3109/09273940903370730.
To identify the microbiological spectrum and visual outcome of bleb-associated endophthalmitis.
The medical records of patients treated for bleb-associated endophthalmitis were reviewed.
Seventy-five patients were identified. Vitreous cultures were positive in 48 (64%) patients. The most common isolates were Streptococcus species in 24 (50%) eyes, gram-negative bacteria in 10 (20.8%) eyes, and Staphylococcus epidermidis in 7 (14.6%) eyes. Good visual outcome was achieved in 33 (44%) patients. On univariate analysis, shorter interval from onset of symptoms and treatment (p = .005), better initial visual acuity (p = .004), clear cornea at presentation (p = .048), isolation of less virulent organisms (p < .001), and absence of diabetes mellitus (p = .048) were significant positive predictors for good visual outcome.
Bleb-associated endophthalmitis is associated with severe visual impairment. Clinical features associated with better visual outcome include early presentation, better presenting visual acuity, clear cornea at presentation, culture of a less virulent organism, and absence of diabetes mellitus.
确定与滤过泡相关的眼内炎的微生物谱和视觉结果。
回顾了接受滤过泡相关眼内炎治疗的患者的病历。
共确定了 75 名患者。48 名（64%）患者的玻璃体培养呈阳性。最常见的分离物为 24 只眼（50%）的链球菌属、10 只眼（20.8%）的革兰氏阴性菌和 7 只眼（14.6%）的表皮葡萄球菌。33 名（44%）患者获得了良好的视觉结果。单因素分析显示，症状和治疗开始的时间间隔较短（p=0.005）、初始视力较好（p=0.004）、表现时角膜透明（p=0.048）、分离出的病原体毒力较弱（p<0.001）和无糖尿病（p=0.048）是良好视觉结果的显著正预测因子。
滤过泡相关眼内炎与严重的视力损害相关。与更好的视觉结果相关的临床特征包括早期就诊、更好的就诊时视力、表现时角膜透明、培养出毒力较弱的病原体以及无糖尿病。
