眼内炎：临床表现、治疗的变化以及早期玻璃体切除术的作用
Endophthalmitis: Changes in Presentation, Management and the Role of Early Vitrectomy.
作者信息
Shao Emily H, Yates William B, Ho I-Van, Chang Andrew A, Simunovic Matthew P
机构信息
Retinal Unit, Sydney Eye Hospital, 8 Macquarie St., Sydney, NSW, 2000, Australia.
Save Sight Institute, Sydney Eye Hospital, University of Sydney, South Block, Sydney, NSW, 2006, Australia.
出版信息
Ophthalmol Ther. 2021 Dec;10(4):877-890. doi: 10.1007/s40123-021-00406-6. Epub 2021 Oct 25.
Abstract
Endophthalmitis is a sight-threatening condition, and its timely and appropriate management is essential in preventing permanent vision loss. Recent changes in clinical practice in endophthalmitis and advances in modern vitreoretinal surgery may limit the applicability of established randomised clinical trial evidence to current management. This review discusses the epidemiology, pathophysiology, changing patient presentation, diagnosis and advances in the management of endophthalmitis, presenting the existing literature on this topic and results from Sydney Eye Hospital.
摘要
眼内炎是一种威胁视力的疾病，及时且恰当的治疗对于预防永久性视力丧失至关重要。眼内炎临床实践的最新变化以及现代玻璃体视网膜手术的进展可能会限制已有的随机临床试验证据在当前治疗中的适用性。本综述讨论了眼内炎的流行病学、病理生理学、不断变化的患者表现、诊断以及治疗进展，介绍了关于该主题的现有文献以及悉尼眼科医院的研究结果。
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本文引用的文献
1
Post-surgical versus post-intravitreal injection endophthalmitis: changing patterns in causative flora.术后与眼内注射后内眼炎：致病菌群的变化模式。
Clin Exp Ophthalmol. 2019 Jan;47(1):57-62. doi: 10.1111/ceo.13345. Epub 2018 Jul 16.
2
Management of bacterial postoperative endophthalmitis and the role of vitrectomy.术后细菌性眼内炎的处理及玻璃体切除术的作用。
Surv Ophthalmol. 2018 Sep-Oct;63(5):677-693. doi: 10.1016/j.survophthal.2018.02.003. Epub 2018 Feb 15.
3
Trends in treatment strategies for suspected bacterial endophthalmitis.疑似细菌性眼内炎治疗策略的趋势
Graefes Arch Clin Exp Ophthalmol. 2018 Apr;256(4):833-838. doi: 10.1007/s00417-018-3910-3. Epub 2018 Feb 7.
4
Predictors of Visual Outcomes and Microbial Profile in Endophthalmitis.眼内炎的视力预后及微生物学特征的预测因素
Ophthalmic Surg Lasers Imaging Retina. 2016 Nov 1;47(11):991-998. doi: 10.3928/23258160-20161031-02.
5
MICROBIOLOGIC SPECTRUM AND VISUAL OUTCOMES OF ACUTE-ONSET ENDOPHTHALMITIS UNDERGOING THERAPEUTIC PARS PLANA VITRECTOMY.接受治疗性玻璃体切割术的急性发作性眼内炎的微生物谱及视力预后
Retina. 2017 Jul;37(7):1246-1251. doi: 10.1097/IAE.0000000000001358.
6
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Eur J Ophthalmol. 2017 Jan 19;27(1):67-73. doi: 10.5301/ejo.5000866. Epub 2016 Sep 13.
7
Comparison of microbiology and visual outcomes of patients undergoing small-gauge and 20-gauge vitrectomy for endophthalmitis.小切口和20G玻璃体切割术治疗眼内炎患者的微生物学及视觉效果比较
Clin Ophthalmol. 2016 Jan 22;10:167-72. doi: 10.2147/OPTH.S95906. eCollection 2016.
8
THE ROLE OF EARLY VITRECTOMY IN THE TREATMENT OF FUNGAL ENDOGENOUS ENDOPHTHALMITIS.早期玻璃体切除术在真菌性内源性眼内炎治疗中的作用
Retin Cases Brief Rep. 2016 Summer;10(3):232-5. doi: 10.1097/ICB.0000000000000238.
9
An in Vitro Experimental Study on the Antimicrobial Activity of Silicone Oil against Anaerobic Bacteria.硅油对厌氧菌抗菌活性的体外实验研究
Ocul Immunol Inflamm. 2016;24(2):173-7. doi: 10.3109/09273948.2014.971973. Epub 2014 Oct 30.
10
Endophthalmitis caused by streptococcal species: clinical settings, microbiology, management, and outcomes.由链球菌属引起的眼内炎：临床情况、微生物学、处理和结局。
Am J Ophthalmol. 2014 Apr;157(4):774-780.e1. doi: 10.1016/j.ajo.2013.12.026. Epub 2014 Jan 10.
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