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亚临床腹主动脉瘤的生长速率——对复查和重新筛查计划的启示

Growth rates of subclinical abdominal aortic aneurysms--implications for review and rescreening programmes.

作者信息

Collin J, Heather B, Walton J

机构信息

University of Oxford, Nuffield Department of Surgery, John Radcliffe Hospital, U.K.

出版信息

Eur J Vasc Surg. 1991 Apr;5(2):141-4. doi: 10.1016/s0950-821x(05)80678-4.

Abstract

One hundred and six patients with abdominal aortic aneurysms (AAAs) of 2.5 to 3.9 cm in anteroposterior diameter were reexamined by ultrasound every 6 months for up to 3 years after diagnosis. Annual growth rates were 0.11 cm +/- 0.03 (mean +/- SE) for AAAs 2.5 to 2.9 cm and 0.29 cm +/- 0.08 for AAAs 3.5 to 3.9 cm (P = 0.002). In 73 patients (69%) the annual rate of increase in diameter was 0.2 cm or less and only 12 aneurysms (11%) grew at more than 0.5 cm per annum. We conclude that: (1) for AAAs less than 4.0 cm diameter remeasurement more often than every 6 months is unnecessary; (2) interval screening (rescreening) for AAAs more frequently than 5 yearly is unlikely to detect sufficient clinically significant aneurysms to be worthwhile.

摘要

对106例腹主动脉瘤(AAA)患者进行了研究,这些患者的腹主动脉瘤前后径在2.5至3.9厘米之间,诊断后每6个月通过超声复查一次,最长持续3年。2.5至2.9厘米的腹主动脉瘤年增长率为0.11厘米±0.03(均值±标准误),3.5至3.9厘米的腹主动脉瘤年增长率为0.29厘米±0.08(P = 0.002)。73例患者(69%)的直径年增长率为0.2厘米或更低,只有12个动脉瘤(11%)每年增长超过0.5厘米。我们得出结论:(1)对于直径小于4.0厘米的腹主动脉瘤,无需每6个月进行一次以上的重新测量;(2)对腹主动脉瘤进行间隔筛查(重新筛查)的频率超过每5年一次,不太可能检测到足够数量具有临床意义的动脉瘤,因此不值得这样做。

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