Montreal University, Fernand-Seguin Research Centre, Philippe-Pinel Institute of Montreal, Montreal, Quebec.
Can J Psychiatry. 2010 Mar;55(3):172-9. doi: 10.1177/070674371005500309.
To identify the clinical specificity of men with severe mental illness (aged 18 to 40 years) by legal status.
Our study compared 85 inmates with 66 involuntarily hospitalized patients (IHPs) and 50 voluntarily hospitalized patients (VHPs) with at least one Axis I diagnosis of psychosis or major affective disorder. Sociodemographics, medical information, and criminal history were drawn from interviews, medical records, and official criminal records. We used the Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders to determine Axis I disorders and antisocial personality disorder (ASPD). Psychopathy was measured with the Psychopathy Checklist--Revised.
We found that inmates had a lower level of schooling (P = 0.001), were more likely to have been in an intimate relationship (P < 0.001), and were less likely to have a psychiatric hospitalization history (P < 0.001), compared with hospitalized patients. Inmates were also more likely to meet criteria for delusional disorders or psychosis not otherwise specified (P < 0.001) and major depression (P = 0.001). IHPs were more likely to meet schizophrenia spectrum disorder criteria (P < 0.001). Inmates had a higher level of comorbidity involving ASPD (P < 0.001), psychopathy (P < 0.001), and substance misuse (P < 0.001). IHPs showed an intermediate level between inmates and VHPs for these comorbid disorders. VHPs had the lowest level of comorbidity with Axis I psychiatric diagnosis.
Our clinical specificity hypothesis was supported: different psychopathological characteristics and social functioning profiles were identified by legal status. Specific integrated treatments should be considered for inmates and IHPs.
通过法律地位确定患有严重精神疾病(18 至 40 岁)的男性的临床特征。
本研究比较了 85 名囚犯、66 名非自愿住院患者(IHPs)和 50 名自愿住院患者(VHPs),这些患者均至少有一个精神分裂症或重性抑郁障碍的轴 I 诊断。社会人口统计学、医疗信息和犯罪史均来自访谈、病历和官方犯罪记录。我们使用精神障碍诊断与统计手册的结构化临床访谈来确定轴 I 障碍和反社会人格障碍(ASPD)。采用修订后的明尼苏达多相人格问卷测查精神病态。
与住院患者相比,我们发现囚犯的受教育程度较低(P=0.001),更有可能处于亲密关系中(P<0.001),且更不可能有精神病住院史(P<0.001)。囚犯也更有可能符合妄想障碍或其他特定的精神病性障碍(P<0.001)和重性抑郁障碍的诊断标准(P=0.001)。IHPs 更有可能符合精神分裂症谱系障碍的诊断标准(P<0.001)。囚犯的 ASPD(P<0.001)、精神病态(P<0.001)和物质使用障碍的合并症发生率更高(P<0.001)。在这些合并症中,IHPs 介于囚犯和 VHPs 之间,表现出中间水平。VHPs 与轴 I 精神科诊断的合并症发生率最低。
我们的临床特异性假设得到了支持:通过法律地位确定了不同的精神病理特征和社会功能特征。囚犯和 IHPs 应考虑采用特定的综合治疗方法。