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Reproducibility of the measurement of ciprofloxacin concentration in bronchial mucosa.

作者信息

Winter J, Sweeney G

机构信息

Department of Respiratory Medicine, Kings Cross Hospital, Dundee, UK.

出版信息

J Antimicrob Chemother. 1991 Mar;27(3):329-33. doi: 10.1093/jac/27.3.329.

DOI:10.1093/jac/27.3.329
PMID:2037538
Abstract

The reproducibility of ciprofloxacin estimations was investigated in duplicate samples of bronchial mucosa from patients undergoing fibreoptic bronchoscopy. At the time of biopsy, venous blood was collected from each patient. Between 3.5 and 5.0 h after dosing, penetration (%) into the mucosa was 162.13 (S.D. 19.77). The correlation coefficient (Pearson's) between duplicate samples was 0.93. The confidence limits (95%) for a single measurement were +/- 1.47 mg/kg.

摘要

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