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Psychosocial distress and somatic symptoms in community subjects with irritable bowel syndrome: a psychological component is the rule.肠易激综合征社区患者的心理社会困扰与躯体症状：心理因素是关键。
Am J Gastroenterol. 2009 Jul;104(7):1772-9. doi: 10.1038/ajg.2009.239. Epub 2009 Jun 2.
2
Will the history and physical examination help establish that irritable bowel syndrome is causing this patient's lower gastrointestinal tract symptoms?病史和体格检查有助于确定肠易激综合征是否是导致该患者下消化道症状的原因吗？
JAMA. 2008 Oct 15;300(15):1793-805. doi: 10.1001/jama.300.15.1793.
3
Chronic pelvic pain in women: still a challenge.女性慢性盆腔疼痛：仍是一项挑战。
BJU Int. 2008 Nov;102(9):1061-5. doi: 10.1111/j.1464-410X.2008.07771.x. Epub 2008 Jun 6.
4
Somatic comorbidities of irritable bowel syndrome: a systematic analysis.肠易激综合征的躯体共病：一项系统分析
J Psychosom Res. 2008 Jun;64(6):573-82. doi: 10.1016/j.jpsychores.2008.02.021. Epub 2008 Apr 28.
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Risk factors for chronic constipation and a possible role of analgesics.慢性便秘的风险因素及镇痛药的潜在作用。
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Comorbidity in irritable bowel syndrome.肠易激综合征中的共病情况。
Am J Gastroenterol. 2007 Dec;102(12):2767-76. doi: 10.1111/j.1572-0241.2007.01540.x. Epub 2007 Sep 26.
7
Irritable bowel syndrome and chronic pelvic pain: a singular or two different clinical syndrome?肠易激综合征与慢性盆腔疼痛：一种单一的还是两种不同的临床综合征？
World J Gastroenterol. 2007 Jul 7;13(25):3446-55. doi: 10.3748/wjg.v13.i25.3446.
8
Psychosocial aspects of the functional gastrointestinal disorders.功能性胃肠疾病的社会心理因素
Gastroenterology. 2006 Apr;130(5):1447-58. doi: 10.1053/j.gastro.2005.11.057.
9
Depression in women with endometriosis with and without chronic pelvic pain.患有和未患有慢性盆腔疼痛的子宫内膜异位症女性的抑郁症
Acta Obstet Gynecol Scand. 2006;85(1):88-92. doi: 10.1080/00016340500456118.
10
Factors predisposing women to chronic pelvic pain: systematic review.女性慢性盆腔疼痛的易感因素：系统评价
BMJ. 2006 Apr 1;332(7544):749-55. doi: 10.1136/bmj.38748.697465.55. Epub 2006 Feb 16.

肠易激综合征与慢性盆腔痛：一项基于人群的研究。

Irritable bowel syndrome and chronic pelvic pain: a population-based study.

机构信息

Department of Medicine, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.

出版信息

J Clin Gastroenterol. 2010 Nov-Dec;44(10):696-701. doi: 10.1097/MCG.0b013e3181d7a368.

DOI:10.1097/MCG.0b013e3181d7a368
PMID:20375730
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3935283/
Abstract

BACKGROUND

Women with irritable bowel syndrome (IBS) frequently report chronic pelvic pain, however, it is still unanswered whether these are truly separate entities. IBS negatively impacts on quality of life, but the impact of IBS on sexual function is not clear.

GOALS

We aimed to (1) describe the impact of IBS on sexual function, and (2) evaluate the association between pelvic pain and IBS, and in particular identify if there are unique characteristics of the overlap group.

STUDY

The Talley Bowel Disease Questionnaire was mailed to an age- and gender-stratified random sample of 1031 Olmsted County, Minnesota residents aged 30 to 64 years. Manning (at least 2 of 6 positive) and Rome criteria (Rome I and modified Rome III) were used to identify IBS. Pelvic pain was assessed by a single item. Somatization was assessed by the valid somatic symptom checklist.

RESULTS

Overall 648 (69%) of 935 eligible participants responded (mean age 52 years, 52% female). Self-reported sexual dysfunction was rare (0.9%; 95% CI 0.3-2.0%). Among women, 20% (95% CI 16-24%) reported pain in the pelvic region; 40% of those with pelvic pain met IBS by Manning, or Rome criteria. IBS and pelvic pain occurred together more commonly than expected by chance (P<0.01). The overall somatization score (and specifically the depression and dizziness item scores) predicted IBS-pelvic pain overlap versus either IBS alone or pelvic pain alone.

CONCLUSION

In a subset with pelvic pain, there is likely to be a common underlying psychologic process (somatization) that explains the link to IBS.

摘要

背景

患有肠易激综合征（IBS）的女性常报告慢性盆腔疼痛，但这些是否确实是两个独立的实体仍未得到解答。IBS 会对生活质量产生负面影响，但 IBS 对性功能的影响尚不清楚。

目的

我们旨在（1）描述 IBS 对性功能的影响，以及（2）评估盆腔疼痛与 IBS 之间的关联，特别是确定重叠组是否存在独特的特征。

研究

Manning（至少有 6 个阳性中的 2 个）和 Rome 标准（Rome I 和改良 Rome III）用于识别 IBS。通过单一项目评估盆腔疼痛。采用有效的躯体症状清单评估躯体化。

结果

在符合条件的 935 名参与者中，共有 648 名（69%）（平均年龄 52 岁，52%为女性）做出了回应。自我报告的性功能障碍罕见（0.9%；95%CI 0.3-2.0%）。在女性中，20%（95%CI 16-24%）报告盆腔区域疼痛；40%有盆腔疼痛的患者符合 Manning 或 Rome 标准的 IBS 诊断。IBS 和盆腔疼痛同时发生的频率比预期的机会更高（P<0.01）。总体躯体化评分（特别是抑郁和头晕项目评分）预测了 IBS-盆腔疼痛重叠与 IBS 或盆腔疼痛单独发生的情况。

结论

在有盆腔疼痛的亚组中，可能存在一个共同的潜在心理过程（躯体化），解释了与 IBS 的联系。