Mahale Swapna, Dani Nitin, Ansari Shumaila S, Kale Triveni
Professor and Guide, MGV's KBH Dental College and Hospital, Panchavati, Nashik - 422 003, Maharashtra, India.
J Indian Soc Periodontol. 2009 Jan;13(1):1-5. doi: 10.4103/0972-124X.51886.
Gene therapy is a field of Biomedicine. With the advent of gene therapy in dentistry, significant progress has been made in the control of periodontal diseases and reconstruction of dento-alveolar apparatus.Implementation in periodontics include:-As a mode of tissue engineering with three approaches: cell, protein-based and gene delivery approach.-Genetic approach to Biofilm Antibiotic Resistance.Future strategies of gene therapy in preventing periodontal diseases:-Enhances host defense mechanism against infection by transfecting host cells with an antimicrobial peptide protein-encoding gene.-Periodontal vaccination.Gene therapy is one of the recent entrants and its applications in the field of periodontics are reviewed in general here.
基因治疗是生物医学的一个领域。随着基因治疗在牙科领域的出现，在牙周疾病的控制和牙槽装置的重建方面已经取得了重大进展。在牙周病学中的应用包括：-作为组织工程的一种模式，有三种方法：细胞、基于蛋白质和基因递送方法。-生物膜抗生素耐药性的基因方法。基因治疗预防牙周疾病的未来策略：-通过用抗菌肽蛋白编码基因转染宿主细胞来增强宿主对感染的防御机制。-牙周疫苗接种。基因治疗是最近出现的方法之一，本文在此对其在牙周病学领域的应用进行了综述。
