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合成非晶态和晶态硫化亚铜纳米颗粒,并研究其对不同细胞的比活性。

Syntheses of amorphous and crystalline cupric sulfide nanoparticles and study on the specific activities on different cells.

机构信息

College of Chemistry and Environmental Science, Henan Normal University, Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, Xinxiang 453007, PR China.

出版信息

Chem Commun (Camb). 2010 May 28;46(20):3493-5. doi: 10.1039/c001714k. Epub 2010 Apr 7.

DOI:10.1039/c001714k
PMID:20376385
Abstract

Copper sulfide amorphous nanoparticles and nanocrystals were prepared successfully by a special process. These CuS nanoparticles could specifically and significantly induce the apoptosis and inhibit the proliferation of human cancer cells rather than normal cells. Moreover, the biological activities of these nanoparticles are related to their polymorphs.

摘要

硫化铜非晶纳米颗粒和纳米晶体是通过一种特殊工艺成功制备的。这些 CuS 纳米颗粒能够特异性显著诱导人癌细胞凋亡并抑制其增殖,而对正常细胞则没有影响。此外,这些纳米颗粒的生物学活性与其多晶型有关。

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