Herchline T E, Ayers L W
Department of Internal Medicine, Ohio State University College of Medicine, Columbus 43210.
J Clin Microbiol. 1991 Mar;29(3):419-21. doi: 10.1128/jcm.29.3.419-421.1991.
Consecutive record review over a 63-month period revealed 229 Staphylococcus lugdunensis isolates, or 10.1% of the staphylococcal species that were not Staphylococcus aureus or Staphylococcus epidermidis. A total of 155 S. lugdunensis specimens were isolated from sites over the entire bodies of the 143 patients studied. The most common clinical diagnoses were skin and skin structure infections (55.4%) and blood and vascular catheter infections (17.4%). For 40% of the reviewed specimens, S. lugdunensis was the sole agent isolated, and for 60% of specimens, S. lugdunensis was isolated as part of mixed flora. In only 15.4% of clinically reviewed specimens was S. lugdunensis clearly a culture contaminant or colonizing organism. The pattern of human infection identified in this study emphasizes the predominance of skin and soft tissue S. lugdunensis infections over deep serious infections such as endocarditis, peritonitis, infected hip prosthesis, and osteomyelitis and vascular-associated infections. S. lugdunensis should be included along with S. epidermidis, Staphylococcus haemolyticus, and Staphylococcus saprophyticus as a coagulase-negative species of Staphylococcus pathogenic for humans.
在63个月的时间里进行的连续记录审查显示，有229株路邓葡萄球菌分离株，占非金黄色葡萄球菌或表皮葡萄球菌葡萄球菌种类的10.1%。从143名研究患者的全身部位共分离出155株路邓葡萄球菌标本。最常见的临床诊断是皮肤及皮肤结构感染（55.4%）和血液及血管导管感染（17.4%）。在40%的审查标本中，路邓葡萄球菌是唯一分离出的病原体，在60%的标本中，路邓葡萄球菌是作为混合菌群的一部分被分离出来的。在仅15.4%的临床审查标本中，路邓葡萄球菌显然是培养污染物或定植菌。本研究中确定的人类感染模式强调，与心内膜炎、腹膜炎、感染性髋关节假体、骨髓炎和血管相关感染等深部严重感染相比，皮肤和软组织路邓葡萄球菌感染更为常见。路邓葡萄球菌应与表皮葡萄球菌、溶血葡萄球菌和腐生葡萄球菌一起，作为对人类致病的凝固酶阴性葡萄球菌种类。
