Haile D T, Hughes J, Vetter E, Kohner P, Snyder R, Patel R, Cockerill F R
Mayo Medical School, Mayo Clinic and Foundation, Rochester, Minnesota 55905, USA.
J Clin Microbiol. 2002 Feb;40(2):654-6. doi: 10.1128/JCM.40.2.654-656.2002.
Recent reports associate Staphylococcus lugdunensis with severe infection in humans. The frequency of this microorganism in urine cultures is unknown. Five hundred isolates of coagulase-negative staphylococci (CoNS) were recovered from 4,652 consecutive urine specimens submitted for culture to the Mayo Clinic Microbiology Laboratory. Thirty-one (6%) of 500 isolates of CoNS were identified as S. lugdunensis. In no case was S. lugdunensis isolated in pure culture; 29 (94%) of 31 S. lugdunensis isolates were part of mixed nonpathogenic flora. Medical records were reviewed for 30 of the 31 patients from whom these 31 isolates were isolated. Twenty-one (70%) of the 30 evaluable patients were not treated with antibiotics; the remaining 9 (30%) of 30 patients were treated with antibiotics that may be effective against S. lugdunensis. S. lugdunensis may be an unrecognized yet infrequent cause of urinary tract infection.
近期报告显示路邓葡萄球菌与人类严重感染有关。这种微生物在尿培养中的出现频率尚不清楚。从提交至梅奥诊所微生物实验室进行培养的4652份连续尿液标本中分离出500株凝固酶阴性葡萄球菌（CoNS）。500株CoNS中有31株（6%）被鉴定为路邓葡萄球菌。路邓葡萄球菌均未以纯培养形式分离出来；31株路邓葡萄球菌中有29株（94%）是混合非致病性菌群的一部分。对分离出这31株菌株的31例患者中的30例进行了病历审查。30例可评估患者中有21例（70%）未接受抗生素治疗；其余9例（30%）患者接受了可能对路邓葡萄球菌有效的抗生素治疗。路邓葡萄球菌可能是一种未被认识但不常见的尿路感染病因。
