Fleurette J, Bès M, Brun Y, Freney J, Forey F, Coulet M, Reverdy M E, Etienne J
Centre National de Référence des Staphylocoques, Faculté de Médecine Alexis Carrel, Rue Guillaume Paradin, Lyon, France.
Res Microbiol. 1989 Feb;140(2):107-18. doi: 10.1016/0923-2508(89)90044-2.
The bacteriological characteristics and susceptibility to antimicrobial agents of 108 clinical isolates of Staphylococcus lugdunensis and Staphylococcus schleiferi are described. Fifty out of 108 isolates were considered to be responsible for 16 documented infections, including some severe infections (endocarditis, bacteraemia, osteitis). A number of bacteriological characteristics enabled the identification of these species in the clinical microbiology laboratory: the absence of coagulase and protein A, and the presence of a fibrinogen affinity factor and thermonuclease along with other biochemical characteristics (ornithine and arginine decarboxylases, carbohydrate acidification, novobiocin susceptibility) differentiated these new species from other staphylococci; however, they did not possess virulence markers such as toxins or haemagglutinin, but were haemolytic. In this series, almost all isolates were susceptible to 22 antibiotics and 4 antiseptics representative of the main groups of antimicrobial agents. More information is needed on the ecology and epidemiology of these new opportunistic pathogens.
描述了108株路邓葡萄球菌和施氏葡萄球菌临床分离株的细菌学特征及对抗菌药物的敏感性。108株分离株中有50株被认为导致了16例有记录的感染，包括一些严重感染（心内膜炎、菌血症、骨炎）。一些细菌学特征有助于临床微生物实验室鉴定这些菌种：缺乏凝固酶和蛋白A，存在纤维蛋白原亲和因子和热核酸酶以及其他生化特征（鸟氨酸和精氨酸脱羧酶、碳水化合物酸化、对新生霉素的敏感性）将这些新菌种与其他葡萄球菌区分开来；然而，它们不具有毒素或血凝素等毒力标记，但具有溶血能力。在该系列中，几乎所有分离株对代表主要抗菌药物组的22种抗生素和4种防腐剂敏感。关于这些新的机会性病原体的生态学和流行病学，还需要更多信息。
