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一项多方面干预措施对病情恶化住院患者早期识别和干预效果的前瞻性对照试验。

A prospective controlled trial of the effect of a multi-faceted intervention on early recognition and intervention in deteriorating hospital patients.

机构信息

The Canberra Hospital, Department of Intensive Care, Yamba Drive, Canberra, Garran, Australian Capital Territory, Australia.

出版信息

Resuscitation. 2010 Jun;81(6):658-66. doi: 10.1016/j.resuscitation.2010.03.001. Epub 2010 Apr 7.

Abstract

AIM

To determine whether the introduction of a multi-faceted intervention (newly designed ward observation chart, a track and trigger system and an associated education program, COMPASS) to detect clinical deterioration in patients would decrease the rate of predefined adverse outcomes.

METHODS

A prospective, controlled before-and-after intervention of trial was conducted in all consecutive adult patients admitted to four medical and surgical wards during a 4 month period, 1157 and 985, respectively. A sub-group of patients underwent vital sign and medical review analysis pre-intervention (427) and post-intervention (320). The outcome measures included: number of unplanned admissions to the intensive care unit (ICU), Medical Emergency Team (MET) reviews and unexpected hospital deaths, vital sign documentation frequency and incidence of a medical review following clinical deterioration. This study is registered, ACTRN12609000808246.

RESULTS

Reductions were seen in unplanned admissions to ICU (21/1157 [1.8%] vs. 5/985 [0.5%], p=0.006) and unexpected hospital deaths (11/1157 [1.0%] vs. 2/985 [0.2%], p=0.03) during the intervention period. Medical reviews for patients with significant clinical instability (58/133 [43.6%] vs. 55/79 [69.6%] p<0.001) and number of patients receiving a MET review increased (25/1157 [2.2%] vs. 38/985 [3.9%] p=0.03) during the intervention period. Mean daily frequency of documentation of all vital signs increased during the intervention period (3.4 [SE 0.22] vs. 4.5 [SE 0.17], p=0.001).

CONCLUSION

The introduction of a multi-faceted intervention to detect clinical deterioration may benefit patients through increased monitoring of vital signs and the triggering of a medical review following an episode of clinical instability.

摘要

目的

确定引入多方面干预措施(新设计的病房观察表、跟踪和触发系统以及相关教育计划 COMPASS)以检测患者的临床恶化是否会降低预先设定的不良结局的发生率。

方法

在四个内科和外科病房进行了一项前瞻性、对照前后干预的试验,在 4 个月的时间内分别连续收治了 1157 名和 985 名成年患者。亚组患者在干预前(427 名)和干预后(320 名)进行了生命体征和医疗回顾分析。结局指标包括:计划外转入重症监护病房(ICU)的人数、医疗急救小组(MET)的评估次数和意外医院死亡人数、生命体征记录频率以及临床恶化后的医疗评估发生率。本研究已注册,ACTRN12609000808246。

结果

干预期间 ICU 计划外入院率(21/1157 [1.8%] vs. 5/985 [0.5%],p=0.006)和意外医院死亡率(11/1157 [1.0%] vs. 2/985 [0.2%],p=0.03)有所降低。在有显著临床不稳定的患者中,进行医疗评估的患者比例(58/133 [43.6%] vs. 55/79 [69.6%],p<0.001)和接受 MET 评估的患者数量(25/1157 [2.2%] vs. 38/985 [3.9%],p=0.03)在干预期间增加。干预期间,所有生命体征的记录频率平均值(3.4 [SE 0.22] vs. 4.5 [SE 0.17],p=0.001)每天增加。

结论

引入多方面干预措施以检测临床恶化可能通过增加生命体征监测和在临床不稳定发作后触发医疗评估来使患者受益。

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