乳酸性酸中毒：识别、动力学及相关预后。

Lactic acidosis: recognition, kinetics, and associated prognosis.

机构信息

Division of Pulmonary and Critical Care Medicine, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, UHN 67, Portland, OR 97239, USA.

出版信息

Crit Care Clin. 2010 Apr;26(2):255-83, table of contents. doi: 10.1016/j.ccc.2009.12.007.

DOI:10.1016/j.ccc.2009.12.007

PMID:20381719

Abstract

Lactic acidosis is a common condition encountered by critical care providers. Elevated lactate and decreased lactate clearance are important for prognostication. Not all lactate in the intensive care unit is due to tissue hypoxia or ischemia and other sources should be evaluated. Lactate, in and of itself, is unlikely to be harmful and is a preferred fuel for many cells. Treatment of lactic acidosis continues to be aimed the underlying source.

摘要

乳酸酸中毒是重症监护医生经常遇到的一种情况。乳酸升高和乳酸清除减少对于预后很重要。并非所有 ICU 中的乳酸都是由于组织缺氧或缺血引起的，应该评估其他来源。乳酸本身不太可能有害，而且是许多细胞的首选燃料。乳酸酸中毒的治疗仍然针对潜在的病因。