Department of Botany, University of Ghana, Legon, Ghana.
J Ethnopharmacol. 2010 Jun 16;129(3):367-76. doi: 10.1016/j.jep.2010.04.001. Epub 2010 Apr 9.
Malaria is one of the most important diseases in the world. Because of the devastating nature of the disease there is an urgent need to develop new drugs or vaccines for the treatment, prevention and management of the disease. The objective of the present study was to collect and document information on herbal remedies traditionally used for the treatment of malaria in the Dangme West District of Ghana.
Data was collected from 67 indigenous households in ten communities in the district using a validated questionnaire.
In total, 30 species of plants belonging to 28 genera in 20 families were reported to be used in the preparation of the herbal remedies. Mature leaves were the most (55%) common plant part used and 73.3% of the herbal remedies involved a single plant. Most of the herbal remedies were prepared by boiling and administered orally. The majority (47%) of the species of plants used were collected from their compounds or home gardens.
Knowledge about malaria and treatment practices exists in the study area. Herbal remedies were commonly used by people for the treatment of malaria because they were cost-effective. They are also more accessible. Many of the species of plants used have been documented for the treatment of malaria as well as investigated for their phytochemical and antimalarial and/or antiplasmodial activity confirming the results of previous studies as well as rationalization of their traditional use. Five species of plants used in the study area, namely, Bambusa vulgaris Schrad. ex J.C. Wendl. (Poaceae), Deinbollia pinnata Schum. &Thonn. (Sapindaceae), Elaeis guineensis Jacq. (Arecaceae), Greenwayodendron sp. (Annonaceae) and Solanum torvum Sw (Solanaceae), are documented for the first time for their use in the treatment of malaria. "The result of this study provides the basis for further pharmacological studies on the herbal remedies used".
疟疾是世界上最重要的疾病之一。由于该疾病具有破坏性，因此迫切需要开发新的药物或疫苗来治疗、预防和管理这种疾病。本研究的目的是收集和记录加纳当梅西部地区传统上用于治疗疟疾的草药信息。
使用经过验证的问卷，从该地区的 10 个社区的 67 个土著家庭中收集数据。
共报告了 30 种植物，这些植物属于 20 个科的 28 个属，用于制备草药制剂。成熟叶片是最常见的植物部分（55%），73.3%的草药制剂仅涉及一种植物。大多数草药制剂是通过煮沸和口服给药。大多数植物（47%）是从自家院子或家周围采集的。
研究区域存在有关疟疾和治疗方法的知识。由于草药制剂具有成本效益，并且更容易获得，因此人们通常会使用草药制剂来治疗疟疾。所使用的许多植物物种已被记录用于治疗疟疾，并且已对其进行了植物化学和抗疟及/或抗疟原虫活性的研究，证实了先前研究的结果，并证实了其传统用途的合理性。在研究区域中使用的五种植物，即 Bambusa vulgaris Schrad。ex J.C. Wend.（禾本科）、Deinbollia pinnata Schum。&Thonn.（无患子科）、Elaeis guineensis Jacq.（棕榈科）、Greenwayodendron sp.（番荔枝科）和 Solanum torvum Sw（茄科），首次被记录用于治疗疟疾。“这项研究的结果为进一步研究用于治疗疟疾的草药制剂提供了基础”。
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