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肯尼亚海岸夸勒社区使用的传统抗疟植物疗法药物。

Traditional antimalarial phytotherapy remedies used by the Kwale community of the Kenyan Coast.

作者信息

Muthaura C N, Rukunga G M, Chhabra S C, Mungai G M, Njagi E N M

机构信息

Centre for Traditional Medicine and Drug Research, Kenya Medical Research Institute, PO Box 54840, Nairobi 00200, Kenya.

出版信息

J Ethnopharmacol. 2007 Dec 3;114(3):377-86. doi: 10.1016/j.jep.2007.08.033. Epub 2007 Aug 25.

Abstract

In Kenya, most people especially in rural areas use traditional medicine and medicinal plants to treat many diseases including malaria. Malaria is of national concern in Kenya, in view of development of resistant strains of Plasmodium falciparum to drugs especially chloroquine, which had been effective and affordable. There is need for alternative and affordable therapy. Many antimalarial drugs have been derived from medicinal plants and this is evident from the reported antiplasmodial activity. The aim of the study was to document medicinal plants traditionally used to treat malaria by the Digo community of Kwale district. Traditional health practitioners were interviewed with standardized questionnaires in order to obtain information on medicinal plants traditionally used for management of malaria. Twenty-five species in 21 genera and 16 families were encountered during the study. Celestraceae, Leguminosae and Rubiaceae families represented the species most commonly cited. Three plant species, namely; Maytenus putterlickioides, Warburgia stuhlmannii and Pentas bussei are documented for the first time for the treatment of malaria.

摘要

在肯尼亚,大多数人,尤其是农村地区的人们,使用传统药物和药用植物来治疗包括疟疾在内的多种疾病。鉴于恶性疟原虫对药物尤其是氯喹产生了耐药性,而氯喹曾经有效且价格低廉,疟疾成为肯尼亚全国关注的问题。因此需要替代且价格合理的治疗方法。许多抗疟药物都源自药用植物,这从已报道的抗疟原虫活性中可见一斑。本研究的目的是记录夸莱区迪戈社区传统上用于治疗疟疾的药用植物。通过标准化问卷对传统保健从业者进行访谈,以获取有关传统上用于疟疾治疗的药用植物的信息。研究过程中发现了21个属、16个科的25个物种。天仙子科、豆科和茜草科是被提及最多的科。首次记录了三种植物,即普氏美登木、斯氏沃伯格樟和布氏五星花用于治疗疟疾。

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