COPD 患者吸入疗法的依从性：对生存和加重的影响。

Adherence to inhaled therapy in COPD: effects on survival and exacerbations.

机构信息

Gr T Popa University of Medicine and Pharmacy Iasi, Department of Internal Medicine II-Pulmonary Disease, Pulmonary Disease University Hospital, 30 Dr I Cihac Str, 700115 Iasi, Romania.

出版信息

Expert Rev Pharmacoecon Outcomes Res. 2010 Apr;10(2):115-7. doi: 10.1586/erp.10.10.

DOI:10.1586/erp.10.10

PMID:20384558

Abstract

Evaluation of: Vestbo J, Anderson JA, Calverley PMA et al. Adherence to inhaled therapy, mortality and hospital admission in COPD. Thorax 64, 939-943 (2009). In chronic diseases, adherence to inhaled therapy can impact treatment effectiveness and can influence disease mortality and morbidity. In chronic respiratory diseases in general, and chronic obstructive pulmonary disease (COPD) in particular, adherence to inhaled therapy can potentially influence disease prognosis, as demonstrated in the analyses discussed in this article and a 3-year study assessing the effects of inhaled salmeterol, inhaled fluticasone and an inhaled combination over placebo in patients with moderate-to-severe COPD patients. It is demonstrated that good adherence to inhaled therapy can reduce all-cause mortality and hospital admissions. Such results are very useful in clinical practice to motivate patients to adhere to their inhaled treatment.

摘要

评价

Vestbo J、Anderson JA、Calverley PMA 等人。COPD 患者吸入治疗的依从性、死亡率和住院率。胸 64，939-943（2009 年）。在慢性疾病中，吸入治疗的依从性会影响治疗效果，并会影响疾病的死亡率和发病率。在一般的慢性呼吸系统疾病中，特别是在慢性阻塞性肺疾病（COPD）中，正如本文讨论的分析和一项为期 3 年的研究所示，吸入沙美特罗、吸入氟替卡松和吸入复方制剂与安慰剂相比对中重度 COPD 患者的影响所表明的那样，吸入治疗的依从性可能会影响疾病预后。研究表明，良好的吸入治疗依从性可以降低全因死亡率和住院率。这些结果在临床实践中非常有用，可以激励患者坚持吸入治疗。