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吸入器识别:评估一种用于慢性呼吸道疾病管理中依从性的潜在筛查方法。

Inhaler identification: evaluating a potential screening method for adherence in chronic respiratory disease management.

作者信息

Gomes David Silva, Seixas Carlos, Cravo João

机构信息

. Departamento de Pneumologia do Hospital Infante D. Pedro, Unidade Local de Saúde da Região de Aveiro, Aveiro, Portugal.

. Portucalense University, Research on Economics, Management and Information Technologies, REMIT, Porto, Portugal.

出版信息

J Bras Pneumol. 2025 Sep 8;51(3):e20250393. doi: 10.36416/1806-3756/e20250393. eCollection 2025.

DOI:10.36416/1806-3756/e20250393
PMID:40929494
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12401153/
Abstract

OBJECTIVES

This study explores the relationship between inhaler visual identification, naming, and adherence outcomes, and evaluates the potential of combining these factors into a screening tool for identifying poor adherence.

METHODS

This observational, prospective study included adult patients with COPD, asthma, or asthma+COPD who had been on chronic inhalation therapy for at least the past year. Data were collected through patient interviews and medical records. Adherence was assessed using the Test of Adherence to Inhalers (TAI) questionnaire and prescription records, calculated as the Proportion of Days Covered (PDC). The patients completed a questionnaire to evaluate their ability to visually identify and name their inhalers.

RESULTS

Among the 196 participants, significant differences in adherence levels were observed across the COPD, asthma, and asthma+COPD groups, with COPD patients demonstrating higher adherence rates (p=0.001). Concordance between TAI and PDC was highest in the COPD group (75.0%), compared to the asthma (51.3%) and asthma+COPD (55.5%) groups. Correct naming of inhalers was not significantly correlated with adherence. However, correct inhaler visual identification was associated with better adherence. Incorrect visual identification showed low sensitivity (15.9%) but high specificity (92.6%) for detecting poorly adherent patients.

CONCLUSIONS

The ability to visually identify inhalers was associated with better adherence, while the ability to name inhalers was not. Although incorrect visual identification has limited utility as a screening tool, it may still serve as a rapid and practical method for identifying poorly adherent patients in clinical practice.

摘要

目的

本研究探讨吸入器视觉识别、命名与依从性结果之间的关系,并评估将这些因素结合成一种用于识别依从性差的筛查工具的潜力。

方法

这项观察性前瞻性研究纳入了患有慢性阻塞性肺疾病(COPD)、哮喘或哮喘合并COPD且过去至少一年一直在接受慢性吸入治疗的成年患者。通过患者访谈和病历收集数据。使用吸入器依从性测试(TAI)问卷和处方记录评估依从性,以覆盖天数比例(PDC)计算。患者完成一份问卷以评估他们视觉识别和说出吸入器名称的能力。

结果

在196名参与者中,COPD、哮喘和哮喘合并COPD组的依从性水平存在显著差异,COPD患者的依从率更高(p = 0.001)。与哮喘组(51.3%)和哮喘合并COPD组(55.5%)相比,TAI与PDC之间的一致性在COPD组中最高(75.0%)。吸入器的正确命名与依从性无显著相关性。然而,正确的吸入器视觉识别与更好的依从性相关。错误的视觉识别在检测依从性差的患者方面显示出低敏感性(15.9%)但高特异性(92.6%)。

结论

吸入器的视觉识别能力与更好的依从性相关,而说出吸入器名称的能力则不然。虽然错误的视觉识别作为一种筛查工具的效用有限,但它仍可能是临床实践中识别依从性差的患者的一种快速实用的方法。

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本文引用的文献

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Use and persistence of single and multiple inhaler triple therapy prescribed for patients with COPD in France: a retrospective study on THIN database (OPTI study).法国 COPD 患者使用和坚持单药及多药三联吸入治疗的情况:THIN 数据库的回顾性研究(OPTI 研究)。
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BMJ Open Respir Res. 2021 Aug;8(1). doi: 10.1136/bmjresp-2020-000823.
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Adherence to Therapy in Chronic Obstructive Pulmonary Disease: A Systematic Review.慢性阻塞性肺疾病治疗的依从性:系统评价。
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Int J Chron Obstruct Pulmon Dis. 2019 Feb 19;14:343-352. doi: 10.2147/COPD.S184653. eCollection 2019.
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A Systematic Review of Medication Adherence Thresholds Dependent of Clinical Outcomes.对依赖临床结果的药物依从性阈值的系统评价。
Front Pharmacol. 2018 Nov 20;9:1290. doi: 10.3389/fphar.2018.01290. eCollection 2018.
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Adherence to inhaled therapies of COPD patients from seven Latin American countries: The LASSYC study.来自七个拉丁美洲国家的慢性阻塞性肺疾病患者对吸入疗法的依从性:拉丁美洲慢性阻塞性肺疾病吸入治疗研究(LASSYC研究)
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