Favor J, Crenshaw J W
Mutat Res. 1978 Feb;53(1):21-7. doi: 10.1016/0165-1161(78)90376-x.
An ethyl methanesulfonate (EMS) induced dominant lethal dose response experiment was conducted in strain DBA/1J male mice. Two methods of scoring for dominant lethals, the classic method (dissecting females at mid-pregnancy) and an alternative method (inspection of uterine scars after litters were weaned) were compared. Results indicate that strain DBA/1J has a similar sensitivity to EMS-induced dominant lethals as has been previously reported for other mouse genotypes. Of the two methods used to score dominant lethals, the classic method is more sensitive.
在DBA/1J品系雄性小鼠中进行了甲磺酸乙酯（EMS）诱导的显性致死剂量反应实验。比较了两种显性致死评分方法，经典方法（在妊娠中期解剖雌性小鼠）和另一种方法（在幼崽断奶后检查子宫瘢痕）。结果表明，DBA/1J品系对EMS诱导的显性致死的敏感性与先前报道的其他小鼠基因型相似。在用于评分显性致死的两种方法中，经典方法更敏感。
