Department of Molecular Genetics and Microbiology, Stony Brook University, Stony Brook, NY 11794-5222, USA.
Mol Cell. 2010 Apr 9;38(1):1-2. doi: 10.1016/j.molcel.2010.03.011.
Darieva and coworkers (Darieva et al., 2010) have shown that the repressor Yox1 and the activator Fkh2-Ndd1 associate with opposite sides of the dimeric Mcm1 transcription factor but nevertheless compete for binding; the outcome determines expression of late mitotic genes in yeast.
达列娃等人(Darieva 等人,2010 年)已经表明,阻遏物 Yox1 和激活物 Fkh2-Ndd1 与二聚体 Mcm1 转录因子的两侧结合,但它们仍然竞争结合;结果决定了酵母中晚期有丝分裂基因的表达。