The Carter Center, Atlanta, Georgia, USA.
Br J Ophthalmol. 2010 Jan;94(1):14-9. doi: 10.1136/bjo.2009.165282.
The World Health Organization has called upon member states to eliminate blinding trachoma by 2020 using the SAFE strategy. We aimed to determine the prevalence of trachoma and quantify intervention needs for each aspect of the SAFE (surgery, mass administration of antibiotics, promotion of facial cleanliness and environmental improvements) strategy in Nasarawa and Plateau States, Nigeria.
District-based, household cluster surveys were conducted in all 30 local government areas (LGAs) within the states.
A total of 46 960 persons were examined from 7883 selected households. Prevalence estimates of trachomatous inflammation follicular among children 1-9 years of age ranged from 1.7 to 15.8% by LGA. Trichiasis prevalence among adults varied by LGA from 0 to 2.1% and was more common among women (OR = 1.99, 95% CI 1.3 to 3.1). Access to water within a 30 min round trip was reported by 82.3% of households.
LGA-wide trachoma control interventions are warranted in seven LGAs targeting: 5409 persons for surgery to correct trichiasis, 778 698 persons to receive at least three rounds of mass antibiotic distribution, 855 villages in which to promote face-washing and sanitation, and 102 751 households for latrine construction. These mapping surveys demonstrate an example of evidence-based programme planning necessary for measuring progress towards achieving the GET 2020 objective and can be replicated in other areas yet to be mapped for trachoma.
世界卫生组织呼吁成员国在 2020 年前采用 SAFE 策略消除致盲性沙眼。我们旨在确定尼日利亚纳萨拉瓦州和高原州各 SAFE(手术、大规模抗生素投药、促进面部清洁和改善环境卫生)策略方面的沙眼患病率,并量化干预需求。
在州内所有 30 个地方政府区进行了以区为基础的家庭整群调查。
从 7883 户选定家庭中检查了共计 46960 人。1-9 岁儿童滤泡性沙眼感染的患病率估计值因地方政府区而异,范围为 1.7%至 15.8%。成人倒睫的患病率因地方政府区而异,范围为 0%至 2.1%,且女性更为常见(OR=1.99,95%CI 1.3-3.1)。82.3%的家庭报告在 30 分钟往返路程内可以获得水。
需要在七个地方政府区开展全政府范围的沙眼控制干预,目标人群包括:需要手术矫正倒睫的 5409 人;需要接受至少三轮大规模抗生素投药的 778698 人;需要开展面部清洁和卫生促进的 855 个村庄;以及需要修建厕所的 102751 户家庭。这些绘图调查展示了一种基于证据的规划方案的范例,对于衡量实现 2020 年全球根除目标的进展情况是必要的,并且可以在其他尚未进行沙眼绘图的地区进行复制。