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[有症状和无症状HIV感染者中乙型肝炎和丁型肝炎的血清学标志物]

[Serological markers of hepatitis b and hepatitis d among individuals with symptomatic and asymptomatic HIV infection].

作者信息

Radkowski M, Goch A, Laskus T, Babiuch L, Slusarczyk J

机构信息

Zakładu Immunopatologii, Akademii Medycznej w Warszawie.

出版信息

Pol Arch Med Wewn. 1991 Jan;85(1):35-40.

PMID:2038574
Abstract

Serological markers of present or past HBV infection were looked for in 69 persons infected with HIV. 40 out of them were clinically asymptomatic, while 29 showed evidence of clinically overt disease related to HIV infection. Most of them were homo- or bisexual men, prostitutes or intravenous drug abusers. Control group consisted of 247 anti-HIV negative persons with the same behavioural patterns. Serological markers compatible with present or past HBV infection were found in 18 out of 40 (45%) asymptomatic HIV carriers, in 23 out of 29 (79.3%) patients with clinically overt HIV infection, and in 82 out of 247 (33.2%) anti-HIV negative persons from the control group. Presented data show that HIV-infected clinically overt individuals have a higher prevalence of HBV markers than asymptomatic carriers of HIV or persons without anti-HIV belonging to risk groups. Therefore, HBV could be a factor influencing outcome of HIV infection.

摘要

在69名感染HIV的患者中,检测了目前或既往HBV感染的血清学标志物。其中40人临床无症状,而29人有与HIV感染相关的临床显性疾病证据。他们中的大多数是同性恋或双性恋男性、妓女或静脉注射吸毒者。对照组由247名具有相同行为模式的抗HIV阴性者组成。在40名(45%)无症状HIV携带者中的18人、29名临床显性HIV感染患者中的23人以及对照组247名抗HIV阴性者中的82人(33.2%)中,发现了与目前或既往HBV感染相符的血清学标志物。所呈现的数据表明,临床显性HIV感染个体中HBV标志物的患病率高于无症状HIV携带者或属于危险人群的未感染HIV者。因此,HBV可能是影响HIV感染结局的一个因素。

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