挪威饮用水化学成分与癌症及其他一些疾病的死亡率和发病率之间的地理关联。

Geographical associations between drinking water chemistry and the mortality and morbidity of cancer and some other diseases in Norway.

作者信息

Flaten T P, Bølviken B

机构信息

Department of Chemistry, College of Arts and Science, University of Trondheim, Norway.

出版信息

Sci Total Environ. 1991 Feb;102:75-100. doi: 10.1016/0048-9697(91)90308-2.

DOI:10.1016/0048-9697(91)90308-2

PMID:2038666

Abstract

Finished drinking water samples were collected from 384 waterworks that supply 70.9% of the Norwegian population. For 97 municipalities where a majority of the population has had a stable drinking water supply from at least 1965, analytical results for Si, Al, Fe, Mg, Ca, Na, Mn, Cu, Zn, Ba, Sr, K, F-, Cl-, Br-, NO3-, SO4(2-), pH, electrical conductivity, total organic carbon (TOC) and colour are correlated with municipal rates for morbidity of 16 groups of cancer (1975-84), and for mortality of 17 groups of other diseases (1974-83). Several associations are found, some of which may be real, while others are incidental due to the large number of correlations involved. The ecological design of this study implies that cause-and-effect interpretations should be made with great care.

摘要

从为70.9%的挪威人口供水的384家自来水厂采集了已完成检测的水样。对于97个自至少1965年以来大多数人口一直有稳定供水的市镇，硅、铝、铁、镁、钙、钠、锰、铜、锌、钡、锶、钾、氟离子、氯离子、溴离子、硝酸根离子、硫酸根离子、pH值、电导率、总有机碳（TOC）和色度的分析结果与16组癌症（1975 - 1984年）的市镇发病率以及17组其他疾病（1974 - 1983年）的死亡率相关。发现了若干关联，其中一些可能是真实的，而其他一些则是由于涉及大量相关性而具有偶然性。本研究的生态学设计意味着因果解释应格外谨慎。