艾滋病相关综合征患者的肾衰竭

Renal failure in patients with AIDS-related complex.

作者信息

Coleburn N H, Scholes J V, Lowe F C

机构信息

Department of Urology, St. Luke's-Roosevelt Hospital Center, New York, New York.

出版信息

Urology. 1991 Jun;37(6):523-7. doi: 10.1016/0090-4295(91)80316-y.

DOI:10.1016/0090-4295(91)80316-y

PMID:2038784

Abstract

The acquired immune deficiency syndrome (AIDS) and AIDS-related complex (ARC) can be associated with nephropathy and renal failure. As the number of AIDS and ARC patients continues to increase dramatically, urologists will be called upon more frequently to help evaluate these patients for reversible causes of renal failure and to obtain tissue for pathologic diagnosis. Eight patients with ARC and renal failure were recently evaluated. Renal biopsies in 4 patients revealed focal and segmental glomerulosclerosis while 2 others showed proliferative and necrotizing glomerulonephritis with crescents. The implications of this study are that ARC patients with renal failure should be fully evaluated and be considered for long-term dialysis. However, the results of renal biopsies in these patients are unlikely to affect patient treatment.

摘要

获得性免疫缺陷综合征（艾滋病）及艾滋病相关综合征（ARC）可伴有肾病和肾衰竭。随着艾滋病和ARC患者数量急剧持续增加，泌尿科医生将更频繁地被要求协助评估这些患者肾衰竭的可逆病因，并获取组织进行病理诊断。最近对8例ARC合并肾衰竭患者进行了评估。4例患者的肾活检显示局灶节段性肾小球硬化，另外2例显示伴有新月体形成的增殖性坏死性肾小球肾炎。本研究的意义在于，ARC合并肾衰竭患者应进行全面评估，并考虑长期透析。然而，这些患者的肾活检结果不太可能影响患者的治疗。