Chandwani Kavita D, Thornton Bob, Perkins George H, Arun Banu, Raghuram N V, Nagendra H R, Wei Qi, Cohen Lorenzo
J Soc Integr Oncol. 2010 Spring;8(2):43-55.
This study examined the effects of yoga on quality of life (QOL) and psychosocial outcomes in women with breast cancer undergoing radiotherapy. Sixty-one women were randomly assigned to either a yoga or a wait-list group. Yoga classes were taught biweekly during the 6 weeks of radiotherapy. Participants completed measures of QOL, fatigue, benefit finding (finding meaning in the cancer experience), intrusive thoughts, sleep disturbances, depressive symptoms, and anxiety before radiotherapy and then again 1 week, 1 month, and 3 months after the end of radiotherapy. General linear model analyses revealed that compared to the control group, the yoga group reported significantly better general health perception (p = .005) and physical functioning scores (p = .04) 1 week postradiotherapy; higher levels of intrusive thoughts 1 month postradiotherapy (p = .01); and greater benefit finding 3 months postradiotherapy (p = .01). There were no other group differences in other QOL subscales for fatigue, depression, or sleep scores. Exploratory analyses indicated that intrusive thoughts 1 month after radiotherapy were significantly positively correlated with benefit finding 3 months after radiotherapy (r = .36, p = .011). Our results indicated that the yoga program was associated with statistically and clinically significant improvements in aspects of QOL.
本研究考察了瑜伽对接受放射治疗的乳腺癌女性的生活质量（QOL）和心理社会结局的影响。61名女性被随机分配到瑜伽组或等待名单组。在放疗的6周期间，每两周进行一次瑜伽课程教学。参与者在放疗前以及放疗结束后1周、1个月和3个月分别完成生活质量、疲劳、益处发现（在癌症经历中找到意义）、侵入性思维、睡眠障碍、抑郁症状和焦虑的测量。一般线性模型分析显示，与对照组相比，瑜伽组在放疗后1周报告的总体健康感知显著更好（p = .005）和身体功能得分更高（p = .04）；放疗后1个月侵入性思维水平更高（p = .01）；放疗后3个月益处发现更多（p = .01）。在生活质量的其他子量表中，疲劳、抑郁或睡眠得分方面没有其他组间差异。探索性分析表明，放疗后1个月的侵入性思维与放疗后3个月的益处发现显著正相关（r = .36，p = .011）。我们的结果表明，瑜伽项目与生活质量方面具有统计学和临床意义的改善相关。
