来自穿山龙茎叶的菲衍生物。

Phenanthrene derivatives from the stems and leaves of Dioscorea nipponica Makino.

作者信息

Lu Dan, Liu Jin-Ping, Li Hai-Jun, Li Ping-Ya

机构信息

Institute of Frontier Medical Science, Jilin University, Changchun, China.

出版信息

J Asian Nat Prod Res. 2010 Jan;12(1):1-6. doi: 10.1080/10286020903403626.

DOI:10.1080/10286020903403626

PMID:20390736

Abstract

From the CHCl(3)-soluble portion of the 70% EtOH extract of the stems and leaves of Dioscorea nipponica Makino, two new phenanthrenes, 7-hydroxy-2,3,5-trimethoxy-9,10-dihydrophenanthrene (1) and 2,2',7,7'-tetrahydroxy-4,4',6,6'-tetramethoxy-1,1'-biphenanthrenes (2), as well as three known phenanthrenes, 6-methoxycoelonin (3), 4,7-dihydroxy-2,3,6-trimethoxyphenanthrene (4), and 3,7-dihydroxy-2,4,6-trimethoxyphenanthrene (5), were isolated. The structures were determined by means of HR-MS, (1)H NMR, (13)C NMR, and HMBC experiments.

摘要

从薯蓣科植物穿龙薯蓣茎和叶的70%乙醇提取物的三氯甲烷可溶部分中，分离得到两个新的菲类化合物，7-羟基-2,3,5-三甲氧基-9,10-二氢菲（1）和2,2',7,7'-四羟基-4,4',6,6'-四甲氧基-1,1'-联菲（2），以及三个已知的菲类化合物，6-甲氧基异紫堇定（3）、4,7-二羟基-2,3,6-三甲氧基菲（4）和3,7-二羟基-2,4,6-三甲氧基菲（5）。通过高分辨质谱、氢核磁共振、碳核磁共振和异核多键相关实验确定了其结构。