Bacon A E, McGrath S, Fekety R, Holloway W J
Department of Medicine, Medical Center of Delaware, Wilmington 19899.
Antimicrob Agents Chemother. 1991 Mar;35(3):582-3. doi: 10.1128/AAC.35.3.582.
Agar dilution anaerobic susceptibility studies using rifampin, vancomycin, metronidazole, and bacitracin individually and in combination were performed with Clostridium difficile. Fifty-five strains of C. difficile were studied. Eighty-five percent of strains tested (29 of 34) were synergistically inhibited by the combination of bacitracin and rifampin (fractional inhibitory concentration, less than or equal to 0.50).
采用琼脂稀释法,分别单独及联合使用利福平、万古霉素、甲硝唑和杆菌肽,对艰难梭菌进行厌氧药敏试验。共研究了55株艰难梭菌。85% 的受试菌株(34株中的29株)被杆菌肽和利福平联合使用时协同抑制(分数抑菌浓度小于或等于0.50)。