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艰难梭菌的体外协同研究。

In vitro synergy studies with Clostridium difficile.

作者信息

Bacon A E, McGrath S, Fekety R, Holloway W J

机构信息

Department of Medicine, Medical Center of Delaware, Wilmington 19899.

出版信息

Antimicrob Agents Chemother. 1991 Mar;35(3):582-3. doi: 10.1128/AAC.35.3.582.

DOI:10.1128/AAC.35.3.582
PMID:2039211
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC245055/
Abstract

Agar dilution anaerobic susceptibility studies using rifampin, vancomycin, metronidazole, and bacitracin individually and in combination were performed with Clostridium difficile. Fifty-five strains of C. difficile were studied. Eighty-five percent of strains tested (29 of 34) were synergistically inhibited by the combination of bacitracin and rifampin (fractional inhibitory concentration, less than or equal to 0.50).

摘要

采用琼脂稀释法，分别单独及联合使用利福平、万古霉素、甲硝唑和杆菌肽，对艰难梭菌进行厌氧药敏试验。共研究了55株艰难梭菌。85% 的受试菌株（34株中的29株）被杆菌肽和利福平联合使用时协同抑制（分数抑菌浓度小于或等于0.50）。

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Antagonists of nucleic acid derivatives. VIII. Synergism in combinations of biochemically related antimetabolites.核酸衍生物拮抗剂。VIII. 生物化学相关抗代谢物组合中的协同作用。
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Antibiotic-associated colitis due to Clostridium difficile: double-blind comparison of vancomycin with bacitracin.艰难梭菌所致抗生素相关性结肠炎：万古霉素与杆菌肽的双盲比较
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Therapy of relapsing Clostridium difficile-associated diarrhea and colitis with the combination of vancomycin and rifampin.万古霉素与利福平联合治疗复发性艰难梭菌相关性腹泻和结肠炎
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Oral bacitracin vs vancomycin therapy for Clostridium difficile-induced diarrhea. A randomized double-blind trial.口服杆菌肽与万古霉素治疗艰难梭菌感染性腹泻的随机双盲试验
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